Volume 21, Number 11—November 2015
Research
Serotype Changes and Drug Resistance in Invasive Pneumococcal Diseases in Adults after Vaccinations in Children, Japan, 2010–2013
Kimiko Ubukata
, Naoko Chiba, Shigeo Hanada, Miyuki Morozumi, Takeaki Wajima, Michi Shouji, Satoshi Iwata, and Invasive Pneumococcal Diseases Surveillance Study Group
, Naoko Chiba, Shigeo Hanada, Miyuki Morozumi, Takeaki Wajima, Michi Shouji, Satoshi Iwata, and Invasive Pneumococcal Diseases Surveillance Study Group
Table 3
Isolates positive for invasive pneumococcal diseases in adults, by age group, Japan, April 2010–March 2013
| Disease | No. (%) | Mean age, y (±SD) |
p value |
|||||
|---|---|---|---|---|---|---|---|---|
| Total |
19–49 |
50–64 |
65–74 |
75–84 |
>85 |
|||
| Pneumonia* | 375 (52.4) | 33 (39.8) | 66 (42.0) | 103 (49.8) | 105 (60.7) | 68 (71.6) | 74 (14.9) | <0.001 |
| Bacteremia and sepsis† | 172 (24.1) | 20 (24.1) | 42 (26.8) | 55 (26.6) | 34 (19.7) | 21 (22.1) | 70 (15.0) | 0.497 |
| Meningitis | 127 (17.8) | 24 (28.9) | 38 (24.2) | 37 (17.9) | 22 (12.7) | 6 (6.3) | 65 (14.4) | <0.001 |
| Other‡ |
41 (5.7) |
6 (7.2) |
11 (7.0) |
12 (5.8) |
12 (6.9) |
0 |
67 (14.5) |
0.133 |
| Total | 715 | 83 | 157 | 207 | 173 | 95 | 70 (14.9) | |
*Includes empyema (n = 17) and pleuritis (n = 16).
†Bacteremia (n = 39), sepsis (n = 51), severe sepsis (n = 58), and septic shock (n = 24).
‡Cellulitis (n = 7), arthritis (n = 6), spondylitis (n = 4), peritonitis (n = 3), and other conditions.
Page created: October 16, 2015
Page updated: October 16, 2015
Page reviewed: October 16, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
Content Credential