Figure. Yearly changes in number of serotypes and in penicillin resistance in genotypes found in isolates from adults with invasive pneumococcal diseases, Japan, April 2010–March 2013. Serotypes are shown for each of the 3 yearly surveillance periods: April 2010–March 2011, April 2011–March 2012, and April 2012–March 2013. Short tic marks on horizontal axis represent yearly number of isolates for specific serotypes; longer tic marks represent the 3-year surveillance period for each serotype. gPSSP, genotypic penicillin-susceptible Streptococcus pneumoniae; gPISP, genotypic penicillin-intermediate resistant S. pneumoniae; gPRSP, genotypic penicillin-resistant S. pneumoniae. Parentheses enclose abnormal pbp genes that mediate penicillin resistance.