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Volume 21, Number 11—November 2015
CME ACTIVITY - Synopsis

Uncommon Candida Species Fungemia among Cancer Patients, Houston, Texas, USA

Dong Sik Jung1, Dimitrios Farmakiotis12, Ying Jiang, Jeffrey J. Tarrand, and Dimitrios P. KontoyiannisComments to Author 
Author affiliations: Dong-A University College of Medicine, Busan, South Korea (D.S. Jung); The University of Texas MD Anderson Cancer Center, Houston, Texas, USA (D.S. Jung, D. Farmakiotis, Y. Jiang, J.J. Tarrand, D.P. Kontoyiannis); Brigham and Women’s Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts, USA (D. Farmakiotis)

Main Article

Table 2

Characteristics of 37 cancer patients with breakthrough candidemia caused by uncommon Candida species, Houston, Texas, USA

Parameter Patients, no. (%)
Patients with leukemia 33 (89)
Patients with lymphoma or multiple myeloma
 3 (8)
Breakthrough infection while receiving
Amphotericin B 9 (24)
Echinocandin 21 (57)
Caspofungin 6 (29)
Micafungin 10 (48)
Anidulafungin 5 (24)
Azole 6 (16)
Fluconazole 2 (33)
Voriconazole 1 (17)
Itraconazole 3 (50)
Combination*
 1 (3)
Species causing breakthrough fungemia
C. guilliermondii 16 (43)
C. kefyr 8 (22)
C. lusitaniae 7 (19)
C. famata
 6 (16)
Outcome of breakthrough fungemia
Dissemination† 5 (14)
28-day crude mortality rate 28 (76)

*Caspofungin and liposomal amphotericin B.
†Site of dissemination on autopsy: heart, lungs, and liver.

Main Article

1These authors contributed equally to this article.

2Current affiliation: Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.

Page created: October 19, 2015
Page updated: October 19, 2015
Page reviewed: October 19, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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