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Volume 21, Number 12—December 2015
Research

Zoonotic Leprosy in the Southeastern United States

Rahul Sharma, Pushpendra Singh, W.J. Loughry, J. Mitchell Lockhart, W. Barry Inman, Malcolm S. Duthie, Maria T. Pena, Luis A. Marcos, David M. Scollard, Stewart T. Cole, and Richard W. TrumanComments to Author 
Author affiliations: National Hansen’s Disease Program, Baton Rouge, Louisiana, USA (R. Sharma, P. Singh, M.T. Pena, D.M. Scollard, R.W. Truman); Louisiana State University School of Veterinary Medicine, Baton Rouge (R. Sharma, P. Singh, M.T. Pena); Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland (P. Singh, S.T. Cole); Valdosta State University, Valdosta, Georgia, USA (W.J. Loughry, J.M. Lockhart); Florida Department of Health, Merritt Island, Florida, USA (W.B. Inman); Infectious Disease Research Institute, Seattle, Washington, USA (M.S. Duthie); Hattiesburg Clinic, Hattiesburg, Mississippi, USA (L.A. Marcos)

Main Article

Figure 2

Genotyping scheme for Mycobacterium leprae determined by using single-nucleotide polymorphisms (SNPs) and variable number tandem repeat (VNTR) polymorphisms, southeastern United States. Shading indicates the base that differentiates SNP type and subtype of M. leprae. The algorithm used for strain typing of M. leprae is based on specific SNP location and type and VNTR copy number at the various locations identified along the chromosome. After identification of the major SNP subtype, M. leprae is

Figure 2. Genotyping scheme for Mycobacterium leprae determined by using single-nucleotide polymorphisms (SNPs) and variable number tandem repeat (VNTR) polymorphisms, southeastern United States. Shading indicates the base that differentiates SNP type and subtype of M. leprae. The algorithm used for strain typing of M. leprae is based on specific SNP location and type and VNTR copy number at the various locations identified along the chromosome. After identification of the major SNP subtype, M. leprae is further discriminated by using allele numbers at 10 VNTR loci. INS, insertion; DEL, deletion.

Main Article

Page created: October 29, 2015
Page updated: October 29, 2015
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