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Volume 21, Number 3—March 2015
Research

Risk Factors for Death from Invasive Pneumococcal Disease, Europe, 2010

Adoración Navarro-TornéComments to Author , Joana Gomes Dias, Frantiska Hruba, Pier Luigi Lopalco, Lucia Pastore-Celentano, Andrew J. Amato Gauci, and Invasive Pneumococcal Disease Study Group
Author affiliations: Universidad Autónoma de Barcelona, Barcelona, Spain (A. Navarro-Torné); European Centre for Disease Prevention and Control, Stockholm, Sweden (A. Navarro-Torné, J. Gomes Dias, F. Hruba, P.L. Lopalco, L. Pastore-Celentano, A.J. Amato Gauci)

Main Article

Table 2

Associations between invasive pneumococcal disease study variables and death, Europe, 2010*

Variable Outcome
p value†
Nonfatal, no. (%) Fatal, no. (%)
Sex
F 1,147 (91.3) 110 (8.8) 0.631
M
1,498 (90.7)
153 (9.3)
Age group, y
<5 557 (97.7) 13 (2.3)
5–64 1,123 (91.9) 99 (8.1) <0.001
>65
956 (86.3)
152 (13.7)
Clinical presentation
Nonmeningitis 1,571 (91.2) 151 (8.8) <0.001
Meningitis
329 (84.1)
62 (15.9)
Serotype
PCV13-specific‡ 1,155 (93.5) 80 (6.5) <0.001
PCV7 444 (85.9) 73 (14.1)
Non-PCV
1,058 (90.5)
111 (9.5)
Antimicrobial susceptibility
Penicillin
Susceptible 1,815 (93.1) 134 (6.9)
Nonsusceptible§ 106 (86.9) 16 (13.1)
Erythromycin 0.010
Susceptible 1,464 (93.1) 109 (6.9)
Nonsusceptible 451 (92.8) 35 (7.2)

*PCV, pneumococcal conjugate vaccine; PCV7, 7-valent PCV; PCV13, 13-valent PCV;
†Pearson χ2 test.
‡Serotypes contained in PCV13 but not in PCV7.
§Either resistant or intermediate resistance.

Main Article

1Members of the Invasive Pneumococcal Disease Study Group who contributed data are listed at the end of this article.

Page created: April 16, 2015
Page updated: April 16, 2015
Page reviewed: April 16, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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