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Volume 21, Number 5—May 2015
Research

Molecular Epidemiology of Plasmodium falciparum Malaria Outbreak, Tumbes, Peru, 2010–2012

G. Christian BaldevianoComments to Author , Sheila Akinyi Okoth, Nancy Arrospide, Rommell V. Gonzalez, Juan F. Sánchez, Silvia Macedo, Silvia Conde, L. Lorena Tapia, Carola Salas, Dionicia Gamboa, Yeni Herrera, Kimberly A. Edgel, Venkatachalam Udhayakumar, and Andrés G. Lescano
Author affiliations: US Naval Medical Research Unit No. 6, Callao, Peru (G.C. Baldeviano, J.F. Sánchez, S. Macedo, L.L. Tapia, C. Salas, K.A. Edgel, A.G. Lescano); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Akinyi Okoth, V. Udhayakumar); Instituto Nacional de Salud del Peru, Lima, Peru (N. Arrospide); Direccion Regional de Salud de Tumbes, Tumbes, Peru (R.V. Gonzalez, S. Conde); Universidad Peruana Cayetano Heredia, Lima (D. Gamboa); Ministry of Health of Peru, Lima (Y. Herrera)

Main Article

Table 1

Genetic lineage based on 7 neutral microsatellite markers of representative Plasmodium falciparum isolates from malaria outbreak in Tumbes and Amazon Region, Peru, 2010–2012*

Code Collection Date Isolation area Genetic lineage Chromosome location, locus name
6
 4
 7
 6
 10
 2
 3
TA1 Polyα PfPK2 TA109 2490 C2M34 C3M69
MIS 0760 2010 Oct 25 Tumbes BV1 172 183 172 164 84 232 134
MIS 0761 201 Oct 26 Tumbes BV1 172 183 172 164 84 232 134
MIS 1142 2011 Mar 31 Tumbes BV1 172 183 172 164 84 232 134
MIS 1147 2011 Jul 19 Tumbes BV1 172 183 172 164 84 232 134
MIS 1146 2011 Jul 26 Tumbes BV1 172 183 172 164 84 232 134
MIS 1168 2011 Aug 19 Tumbes BV1 172 183 172 164 84 232 134
MIS1280 2011 Aug 27 Tumbes BV1 172 183 172 164 84 232 134
TI-435 2011 Sep 22 Tumbes BV1 172 183 172 164 84 232 134
TIA-4156 2011 Sep 28 Tumbes BV1 169 183 172 164 84 232 134
T3–861 2011 Oct 4 Tumbes BV1 169 183 169 164 84 232 134
TIA-4333 2011 Oct 14 Tumbes BV1 172 183 172 164 84 232 134
MIS1278 2011 Nov 1 Tumbes BV1 172 183 172 164 84 232 134
T3–989 2011 Nov 18 Tumbes BV1 172 183 172 164 84 232 134
M01L1615 2011 Dec 1 Tumbes BV1 169 183 172 164 84 232 134
TIA-434 2011 Dec 1 Tumbes BV1 172 183 172 164 84 232 134
PSSI-205 2011 Dec 27 Corrales BV1 172 183 172 164 84 232 134
Z1–22 2012 Mar 14 Zarumilla BV1 172 183 ND 164 84 232 134
PR-12† Dec 2009 Requena (C) BV1 172 183 172 164 84 232 134
PY013† Mar 2010 Yurimaguas (E) BV1 172 183 172 160 84 232 134
Clonet B† 1999–2000 Loreto (E) B 172 183 172 164 84 226 149
Clonet A† 1999–2000 Loreto (E) A 169 172 166 164 84 240 132
Clonet C† 1999–2000 Loreto (E, W) C 178 164 163 160 80 246 136
Clonet D† 1999–2000 Loreto (E, W) D 178 161 175 160 80 233 122
Clonet E† 1999–2000 Tumbes E 172 148 175 160 74 226 138

*Microsatellite genotypes of all 11 isolates from Requena and 1 of 12 isolates from Yurimaguas were identical to those of the Tumbes outbreak. Only 17 of 54 isolates processed are shown. Isolates were selected to cover the extent of the duration of the outbreak (October 2010–March 2012). ND, not determined.
†Historical microsatellite alleles of clonets A–E found in Peru in 1999–2000 and the BV1 variant found in Loreto in 2009–2010. C, Central Amazon; E, eastern Amazon; W, western Amazon.

Main Article

Page created: April 17, 2015
Page updated: April 17, 2015
Page reviewed: April 17, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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