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Volume 21, Number 8—August 2015
Dispatch

Bartonella spp. and Coxiella burnetii Associated with Community-Acquired, Culture-Negative Endocarditis, Brazil

Rinaldo Focaccia SicilianoComments to Author , Jussara Bianchi Castelli, Alfredo Jose Mansur, Fabiana Pereira dos Santos, Silvia Colombo, Elvira Mendes do Nascimento, Christopher D. Paddock, Roosecelis Araújo Brasil, Paulo Eduardo Neves Ferreira Velho, Marina Rovani Drummond, Max Grinberg, and Tania Mara Varejao Strabelli
Author affiliations: University of São Paulo Medical School, São Paulo, Brazil (R.F. Siciliano, J.B. Castelli, A.J. Mansur, M. Grinberg, T.M.V. Strabelli); Adolfo Lutz Institute, São Paulo (F. Pereira dos Santos, S. Colombo, E.M. Nascimento, R.A. Brasil); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.D. Paddock); State University of Campinas Medical School, Campinas, Brazil (P.E.N.F. Velho, M.R. Drummond)

Main Article

Table

Serologic, immunohistopathologic, and molecular test results for patients with infective endocarditis caused by Bartonella spp. or Coxiella burnetii, Brazil*

C. burnetii Serum anti–phase I IgG
≥800 by IFA§ Immunohistochemical analysis of cardiac valve vegetation
 Microorganism by histologic analysis PCR‡ Q fever endocarditis (6)
Bartonella spp. C. burnetii
11 + Neg + Small gram-negative coccobacilli + Definite
2A criteria
12 + Neg + None + Definite
2A criteria
13 + Neg + None + Definite
2A criteria
14 + NA NA NA + Definite
2B criteria¶

*IFA, immunofluorescence assay; +, positive; Neg, negative; NA, material not available for analysis.
¶Serologic result >6,400 and vegetation on ecocardiography.
†B. henselae or B. quintana.
‡Serum or tissue sample.
§C. burnetii.

Main Article

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Page created: July 15, 2015
Page updated: July 15, 2015
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