Volume 22, Number 12—December 2016
Dispatch
Horizontal Transmission of Chronic Wasting Disease in Reindeer
Table 1
Animal data for reindeer (Rangifer tarandus tarandus) in a study of transmission of CWD*
Group no./animal no. | Genotype codon |
Infectivity source | Exposure route | ||||
---|---|---|---|---|---|---|---|
002 | 129 | 138 | 169 | 176 | |||
1 | |||||||
1 | MV | SG | NS | MV | NN | CWDwtd | Intracranial |
2 | VV | GG | NN | VV | NN | CWDwtd | Intracranial |
3 | VV | GG | NS | VV | ND | CWDwtd | Intracranial |
4 | VV | GG | NS | VV | NN | CWDwtd | Intracranial |
5 |
MV |
SG |
SS |
MV |
ND |
CWDwtd |
Intracranial |
2 | |||||||
6 | VV | GG | NN | VV | NN | CWDelk | Intracranial |
7 | MV | SG | NS | MV | NN | CWDelk | Intracranial |
8 | VV | GG | NS | VV | NN | CWDelk | Intracranial |
9 | VV | GG | NS | VV | ND | CWDelk | Intracranial |
10 |
NA |
SG |
SS |
MV |
NN |
CWDelk |
Intracranial |
3 | |||||||
11 | MV | SG | NS | MV | NN | CWDmd | Intracranial |
12 | VV | GG | NN | VV | NN | CWDmd | Intracranial |
13 | VV | GG | SS | VV | DD | CWDmd | Intracranial |
14 | MV | SG | SS | MV | NN | CWDmd | Intracranial |
15 |
VV |
GG |
NS |
VV |
ND |
CWDmd |
Intracranial |
4 direct | |||||||
16 | VV | GG | NN | VV | NN | Horizontal (CWDwtd) | Cohoused with group 1 |
17 | VV | GG | NN | VV | NN | Horizontal (CWDwtd) | Cohoused with group 1 |
18 | VV | GG | NN | VV | NN | Horizontal (CWDwtd) | Cohoused with group 1 |
19 |
NA |
SG |
NS |
MV |
NN |
Horizontal (CWDwtd) |
Cohoused with group 1 |
4 indirect | |||||||
20 | MM | SS | SS | MM | NN | Horizontal (CWDmd) | Housed adjacent to group 3 |
21 |
VV |
GG |
NN |
VV |
NN |
Horizontal (CWDmd) |
Housed adjacent to group 3 |
4 neg. controls | |||||||
22 | VV | GG | NS | VV | NN | NA | NA |
23 | MV | SG | SS | MV | NN | NA | NA |
*CWD, chronic wasting disease; D, aspartic acid; G, glycine; horizontal, horizontal transmission; M, methionine; md, mule deer (Odocoileus hemionus); N, asparagine; NA, not applicable; neg., negative; S, serine; V, valine; wtd, white-tailed deer (Odocoileus virginianus).
1Deceased.