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Volume 22, Number 12—December 2016

Dispatch

Horizontal Transmission of Chronic Wasting Disease in Reindeer

S. Jo Moore, Robert Kunkle, M. Heather West Greenlee, Eric Nicholson, Jürgen Richt, Amir Hamir1, W. Ray Waters, and Justin GreenleeComments to Author 
Author affiliations: US Department of Agriculture, Ames, Iowa, USA (S.J. Moore, R. Kunkle, E. Nicholson, J. Richt, A. Hamir, W.R. Waters, J. Greenlee):; Iowa State University, Ames (M.H. West Greenlee)

Main Article

Table 1

Animal data for reindeer (Rangifer tarandus tarandus) in a study of transmission of CWD*

Group no./animal no. Genotype codon
Infectivity source Exposure route
002 129 138 169 176
1
1 MV SG NS MV NN CWDwtd Intracranial
2 VV GG NN VV NN CWDwtd Intracranial
3 VV GG NS VV ND CWDwtd Intracranial
4 VV GG NS VV NN CWDwtd Intracranial
5
MV
SG
SS
MV
ND
CWDwtd
Intracranial
2
6 VV GG NN VV NN CWDelk Intracranial
7 MV SG NS MV NN CWDelk Intracranial
8 VV GG NS VV NN CWDelk Intracranial
9 VV GG NS VV ND CWDelk Intracranial
10
NA
SG
SS
MV
NN
CWDelk
Intracranial
3
11 MV SG NS MV NN CWDmd Intracranial
12 VV GG NN VV NN CWDmd Intracranial
13 VV GG SS VV DD CWDmd Intracranial
14 MV SG SS MV NN CWDmd Intracranial
15
VV
GG
NS
VV
ND
CWDmd
Intracranial
4 direct
16 VV GG NN VV NN Horizontal (CWDwtd) Cohoused with group 1
17 VV GG NN VV NN Horizontal (CWDwtd) Cohoused with group 1
18 VV GG NN VV NN Horizontal (CWDwtd) Cohoused with group 1
19
NA
SG
NS
MV
NN
Horizontal (CWDwtd)
Cohoused with group 1
4 indirect
20 MM SS SS MM NN Horizontal (CWDmd) Housed adjacent to group 3
21
VV
GG
NN
VV
NN
Horizontal (CWDmd)
Housed adjacent to group 3
4 neg. controls
22 VV GG NS VV NN NA NA
23 MV SG SS MV NN NA NA

*CWD, chronic wasting disease; D, aspartic acid; G, glycine; horizontal, horizontal transmission; M, methionine; md, mule deer (Odocoileus hemionus); N, asparagine; NA, not applicable; neg., negative; S, serine; V, valine; wtd, white-tailed deer (Odocoileus virginianus).

Main Article

1Deceased.

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