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Volume 22, Number 12—December 2016
CME ACTIVITY - Research

Electrolyte and Metabolic Disturbances in Ebola Patients during a Clinical Trial, Guinea, 2015

Johan van GriensvenComments to Author , Elhadj Ibrahima Bah, Nyankoye Haba, Alexandre Delamou, Bienvenu Salim Camara, Kadio Jean-Jacques Olivier, Hilde De Clerck, Helena Nordenstedt, Malcolm G. Semple, Michel Van Herp, Jozefien Buyze, Maaike De Crop, Steven Van Den Broucke, Lutgarde Lynen, Anja De Weggheleire, and the Ebola-Tx Consortium
Author affiliations: Institute of Tropical Medicine, Antwerp, Belgium (J. van Griensven, J. Buyze, M. De Crop, S. Van Den Broucke, L. Lynen, A. De Weggheleire); Donka National Hospital, Conakry, Guinea (E.I. Bah); National Blood Transfusion Center, Conakry (N. Haba, B.S. Camara, K.J.-J. Olivier); National Center for Training and Research in Rural Health of Maferinyah, Forecariah, Guinea (A. Delamou); Médecins Sans Frontières, Brussels, Belgium (H. De Clerck, H. Nordenstedt, M. Van Herp); University of Liverpool, Liverpool, United Kingdom (M.G. Semple)

Main Article

Table 4

Predicted and observed deaths across risk categories among 77 Ebola patients recruited for the Ebola-Tx trial, according to the POC+ model, Conakry, Guinea, 2015*†

Death risk category (predicted), % Total no. patients (column %) No. deaths observed (row %) No. deaths predicted (row %)
0–4.9 28 (36.4) 1 (3.6) 0.4 (1.5)
5.0–19.9 14 (18.2) 1 (7.1) 1.7 (12.3)
20.0–49.9 11 (14.3) 4 (36.4) 3.7 (34.0)
50.0–79.9 7 (9.1) 4 (57.1) 4.4 (63.5%)
80.0–100 17 (22.1) 17 (100.0) 16.7 (98.1)

*One recruited patient was excluded because of a missing Ct value. Ct, cycle threshold; POC, point-of-care.
†POC+ model includes 3 POC measurements (blood creatinine, calcium, and hemoglobin) plus the cycle threshold value of the diagnostic Ebola PCR result and the age of the patient.

Main Article

Page created: November 17, 2016
Page updated: November 17, 2016
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