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Volume 22, Number 8—August 2016

Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014

Negar AliabadiComments to Author , Kevin Messacar, Daniel M. Pastula, Christine C. Robinson, Eyal Leshem, James Sejvar, W. Allan Nix, M. Steven Oberste, Daniel R. Feikin, and Samuel R. Dominguez
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (N. Aliabadi, E. Leshem, J.J. Sejvar, W.A. Nix, M.S. Oberste, D.R. Feikin); Children’s Hospital Colorado, Aurora, Colorado, USA (K. Messacar, C.C. Robinson, S.R. Dominguez); Centers for Disease Control and Prevention, Fort Collins, Colorado, USA (D.M. Pastula); University of Colorado Denver, Aurora (D.M. Pastula)

Main Article

Table 4

EV-D68 association with acute neurologic disease compared with that of RPP-tested and BP–tested controls, adjusted models*

RPP-tested controls†
BP-tested controls‡
OR (95% CI)
p value
OR (95% CI)
p value
EV-D68 12.9 (2.5–76.4)† 0.002 5.7 (1.3–25.5‡ 0.02
EV/RV excluding EV-D68 6.9 (0.8–66.0)§ 0.08 2.5 (0.4–13.9)¶ 0.30

*Of 13 cases of neurologic disease identified in Colorado during the outbreak period, only 12 provided nasopharyngeal specimens for analysis. RPP models were adjusted for age, time to specimen collection, epidemiologic week of sample collection. B. pertussis models were adjusted for presence of fever, type of specimen collected, and epidemiologic week of specimen collection. BP, Bordetella pertussis; EV, enterovirus; OR, odds ratio; RPP, respiratory pathogen panel; RV, rhinovirus.
†n = 102.
‡n = 226.
§n = 96.
¶n = 195.

Main Article

Page created: July 15, 2016
Page updated: July 15, 2016
Page reviewed: July 15, 2016
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