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Volume 23, Number 12—December 2017

Fatal Outbreak in Tonkean Macaques Caused by Possibly Novel Orthopoxvirus, Italy, January 20151

Giusy Cardeti2Comments to Author , Cesare Ernesto Maria Gruber2, Claudia Eleni, Fabrizio Carletti, Concetta Castilletti, Giuseppe Manna, Francesca Rosone, Emanuela Giombini, Marina Selleri, Daniele Lapa, Vincenzo Puro, Antonino Di Caro, Raniero Lorenzetti, Maria Teresa Scicluna, Goffredo Grifoni, Annapaola Rizzoli, Valentina Tagliapietra, Lorenzo De Marco, Maria Rosaria Capobianchi, and Gian Luca Autorino
Author affiliations: Istituto Zooprofilattico Sperimentale del Lazio e della Toscana M. Aleandri, Rome, Italy (G. Cardeti, C. Eleni, G. Manna, F. Rosone, R. Lorenzetti, M.T. Scicluna, G. Grifoni, G.L. Autorino); L, Spallanzani National Institute of Infectious Diseases, Rome (C.E.M. Gruber, F. Carletti, C. Castilletti, E. Giombini, M. Selleri, D. Lapa, V. Puro, A. Di Caro, M.R. Capobianchi); Fondazione Edmund Mach di San Michele all’Adige, Trento, Italy (A. Rizzoli, V. Tagliapietra); Parco Faunistico Piano dell'Abatino, Poggio San Lorenzo, Italy (L. De Marco)

Main Article

Table 3

Serologic analysis of serum samples from nonhuman primate species housed at animal sanctuary, Italy, January 2015*

Species IFA IgM test, no. positive/no. total (%) IgM titer† IFA IgG test, no. positive/no. total (%) IgG titer,† range
Tonkean macaque (Macaca tonkeana) 0/30 Negative 8/30 1:40−1: 640
Cynomolgus macaque (M. fascicularis) 0/11 Negative 3/11 1:20−1:160
Barbary macaque (M. sylvanus) 2/12 1:20 2/12 1:20
Rhesus macaque (M. mulatta) 0/1 Negative 1/1 1:80
Japanese macaque (M. fuscata) 0/2 Negative 2/2 1:80
Tufted capuchin (Sapajus apella) 0/4 Negative 2/4 1:20
Grivet (Cercopithecus aethiops) 0/1 Negative 0/1 Negative
Hamadryas baboon (Papio hamadryas)
Total 2/62 (3.22) 18/62 (29.03)

*IFA, immunofluorescence antibody.
†Threshold dilution was 1:20.

Main Article

1Preliminary results from this study were presented at the Xth International Congress of the European Society for Veterinary Virology; August 31–September 3, 2015; Montpellier, France.

2These first authors were co–principal investigators who contributed equally to this article.

Page created: November 16, 2017
Page updated: November 16, 2017
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