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Volume 23, Number 2—February 2017
Research

Spread and Evolution of Respiratory Syncytial Virus A Genotype ON1, Coastal Kenya, 2010–2015

James R. OtienoComments to Author , Everlyn M. Kamau, Charles N. Agoti, Clement Lewa, Grieven Otieno, Ann Bett, Mwanajuma Ngama, Patricia A. Cane, and D. James Nokes
Author affiliations: Kenya Medical Research Institute (KEMRI)–Wellcome Trust Research Programme, Kilifi, Kenya (J.R. Otieno, E.M. Kamau, C.N. Agoti, C. Lewa, G. Otieno, A. Bett, M. Ngama, D.J. Nokes); Pwani University, Kilifi (C.N. Agoti); Public Health England, Salisbury, UK (P.A. Cane); University of Warwick, Coventry, UK (D.J. Nokes)

Main Article

Table 1

Demographic and clinical characteristics of cases of pneumonia caused by respiratory syncytial virus A genotypes ON1 and GA2 in children admitted to Kilifi County Hospital, September 2010–August 2015*

Characteristic Genotype, no. (%)
ON1 GA2 Total
Age, y
<1 223 (85.4) 158 (87.3) 381 (86.2)
>1
38 (14.6)
23 (12.7)
61 (13.8)
Sex
F 118 (45.2) 70 (38.6) 188 (42.5)
M
143 (54.8)
111 (61.3)
254 (57.5)
Cough
No 5 (1.9) 4 (2.2) 9 (2.0)
Yes
256 (98.1)
177 (97.8)
433 (98.0)
Breathing difficulty
No 15 (5.8) 3 (1.7) 18 (4.1)
Yes
246 (94.3)
178 (98.3)
423 (95.9)
Chest wall indrawing
No 6 (2.3) 6 (3.3) 12 (2.7)
Yes
255 (97.7)
175 (96.7)
430 (97.3)
Inability to feed
No 211 (81.2) 165 (91.2) 376 (85.3)
Yes
49 (18.9)
16 (8.8)
65 (14.7)
Oxygen saturation, %
>90 214 (82.0) 144 (79.6) 358 (81.0)
<90
47 (18.0)
37 (20.4)
84 (19.0)
Prostration/unconsciousness
No 240 (92.0) 172 (95) 412 (93.2)
Yes
21 (8.0)
9 (5.0)
30 (6.8)
Pneumonia status
Severe† 203 (77.8) 137 (75.7) 340 (76.9)
Very severe‡
58 (22.2)
44 (24.3)
102 (23.1)
Hospital stay, d
1–4 160 (62.0) 101 (55.8) 261 (59.4)
>4
98 (38.0)
80 (44.2)
178 (40.5)
Outcome
Survived 250 (96.9) 177 (97.8) 427 (97.3)
Died 8 (3.1) 4 (2.2) 12 (2.7)

*The denominator was 442 samples but for some of the features it ranged from 439 to 442
†[Cough or difficulty in breathing] and chest wall indrawing
‡[Cough or difficulty in breathing] and hypoxic or prostrate/unconscious.

Main Article

Page created: January 17, 2017
Page updated: January 17, 2017
Page reviewed: January 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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