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Volume 23, Number 3—March 2017

Zoonotic Transmission of mcr-1 Colistin Resistance Gene from Small-Scale Poultry Farms, Vietnam

Nguyen Vinh TrungComments to Author , Sébastien Matamoros, Juan J. Carrique-Mas, Nguyen Huu Nghia, Nguyen Thi Nhung, Tran Thi Bich Chieu, Ho Huynh Mai, Willemien van Rooijen, James Campbell, Jaap A. Wagenaar, Anita Hardon, Nguyen Thi Nhu Mai, Thai Quoc Hieu, Guy Thwaites, Menno D. de Jong, Constance Schultsz1, and Ngo Thi Hoa1
Author affiliations: University of Amsterdam, Amsterdam, the Netherlands (N.V. Trung, S. Matamoros, W. van Rooijen, A. Hardon, M.D. de Jong, C. Schultsz); Amsterdam Institute for Global Health and Development, Amsterdam (N.V. Trung, S. Matamoros, C. Schultsz); Centre for Tropical Medicine, Ho Chi Minh City, Vietnam (N.V. Trung, J.J. Carrique-Mas, N.H. Nghia, N.T. Nhung, T.T.B. Chieu, J. Campbell, G. Thwaites, C. Schultsz, N.T. Hoa); University of Oxford, Oxford, UK (J.J. Carrique-Mas, J. Campbell, G. Thwaites, N.T. Hoa); Sub-Department of Animal Health, My Tho, Vietnam (H.H. Mai, T.Q. Hieu); Utrecht University, Utrecht, the Netherlands (J.A. Wagenaar); Central Veterinary Institute of Wageningen University & Research, Lelystad, the Netherlands (J.A. Wagenaar); Preventive Medicine Center, My Tho (N.T.N. Mai)

Main Article

Table 2

Multivariate analysis of risk factors associated with fecal colonization with mcr-1–carrying bacteria in small-scale chicken farms (N = 94) and in humans (N = 440), Vietnam, 2012–2013*

No. tested
No. mcr-1–positive
OR (95% CI)
p value
Small-scale chicken farms
Age of chickens
Chickens <20.5 weeks old 47 32 21.3 (5.8–78.5) <0.001
Chickens ≥20.5 weeks old 47 8 Referent
Use of colistin
5.1 (1.4–18.8)
Urban persons† 88 8 Referent
Rural persons† 173 31 2.1 (0.9–5.0) 0.075
Farmers exposed to mcr-1–negative chickens 91 16 1.8 (0.7–4.7) 0.205
Farmers exposed to mcr-1–positive chickens 88 29 5.3 (2.2–12.7) <0.001

*OR, odds ratio.
†Not involved in poultry farming.

Main Article

1These authors contributed equally to this article.

Page created: February 17, 2017
Page updated: February 17, 2017
Page reviewed: February 17, 2017
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