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Volume 23, Number 3—March 2017
CME ACTIVITY - Synopsis

Three Cases of Neurologic Syndrome Caused by Donor-Derived Microsporidiosis

Rachel SmithComments to Author , Atis Muehlenbachs, Joanna Schaenmann, Sanjiv Baxi, Sophia Koo, Dianna Blau, Peter Chin-Hong, Anna R. Thorner, Matthew J. Kuehnert, Kristina Wheeler, Alexis Liakos, Jonathan W. Jackson, Theresa Benedict, Alexandre J. da Silva, Jana M. Ritter, Dominique Rollin, Maureen Metcalfe, Cynthia S. Goldsmith, Govinda S. Visvesvara, Sridhar V. Basavaraju, and Sherif Zaki
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (R.M. Smith, A. Muehlenbachs, D. Blau, M.J. Kuehnert, J.W. Jackson, T. Benedict, A.J. da Silva, J.M. Ritter, D. Rollin, M. Metcalfe, C.S. Goldsmith, G.S. Visvesvara, S.V. Basavaraju, S. Zaki); University of California, Los Angeles, California, USA (J. Schaenmann); University of California, San Francisco, California, USA (S. Baxi, P. Chin-Hong); Brigham and Women’s Hospital, Boston, Massachusetts, USA (S. Koo, A.R. Thorner, A. Liakos); Harvard Medical School, Boston (S. Koo, A.R. Thorner, A. Liakos); OneLegacy, Los Angeles (K. Wheeler)

Main Article

Table 1

Infectious disease testing performed for 3 transplant recipients with donor-derived microsporidiosis

Pathogen All recipients Right kidney recipient Left kidney/heart recipient Liver recipient
Bacterial
 Bacterial culture (blood, urine)
 Mycoplasma Borrelia burgdorferi Treponema pallidum
Mycobacterium tuberculosis Anaplasma/Ehrlichia
Borrelia burgdorferi Treponema pallidum
Brucella spp. Tropheryma whipplei
Rickettsia spp.
Pneumocystis jiroveci
Legionella spp.
Viral Cytomegalovirus Enterovirus Enterovirus None
Herpes simplex virus Lymphocytic choriomeningitis Adenovirus
Epstein-Barr virus Measles virus Lymphocytic choriomeningitis
Parvovirus JC virus Measles virus
HIV Human herpesvirus-6 JC virus
Viral fecal cultures Human herpesvirus-6
BK virus
Human T-cell lymphotropic virus
Meningoencephalitis panel*
Fungal/parasitic/other Cryptococcus spp. Coccidioides spp. (1→3)β-D-glucan Toxoplasma gondii
Aspergillus spp. Galactomannan
Strongyloides spp. Coccidioides spp.
Cryptococcus spp.
Schistosoma spp. Toxoplasma gondii
Babesia spp. Babesia spp.
14–3-3 testing for prion disease (cerebrospinal fluid)

*Panel contains the following viruses: West Nile, Lacrosse, Eastern equine encephalitis, St. Louis encephalitis, Western equine encephalitis, lymphocytic choriomeningitis, herpex simplex 1 and 2, adenovirus, influenza A and B, measles, mumps, varicella, coxsackie A and B, echovirus, cytomegalovirus.

Main Article

Page created: February 15, 2017
Page updated: February 15, 2017
Page reviewed: February 15, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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