Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 23, Number 4—April 2017

Dispatch

Detection and Molecular Characterization of Zoonotic Poxviruses Circulating in the Amazon Region of Colombia, 2014

Jose A. Usme-Ciro, Andrea Paredes, Diana M. Walteros, Erica Natalia Tolosa-Pérez, Katherine Laiton-Donato, Maria del Carmen Pinzón, Brett W. Petersen, Nadia F. Gallardo-Romero, Yu Li, Kimberly Wilkins, Whitni Davidson, Jinxin Gao, Nishi Patel, Yoshinori Nakazawa, Mary G. Reynolds, P. S. Satheshkumar, Ginny L. Emerson, Andrés Páez-MartínezComments to Author , and Andrés Páez Martínez.
Author affiliations: Instituto Nacional de Salud, Bogotá, Colombia (J.A. Usme-Ciro, A. Paredes, D.M. Walteros, E.N. Tolosa-Pérez, K. Laiton-Donato, A. Páez-Martínez); Universidad Cooperativa de Colombia, Santa Marta, Colombia (J.A. Usme-Ciro); Laboratorio Departamental de Salud de Caquetá, Caquetá, Colombia (M. del Carmen Pinzón); Centers for Disease Control and Prevention, Atlanta, USA (B.W. Petersen, N.F. Gallardo-Romero, Y. Li, K. Wilkins, W. Davidson, J. Gao, N. Patel, Y. Nakazawa, M.G. Reynolds, P.S. Satheshkumar, G.L. Emerson); Universidad de La Salle, Bogotá (A. Páez-Martínez)

Main Article

Table

Orthopoxvirus IgG and IgM antibodies and poxvirus genome detection in lesion and serum samples*

Patient no. Identification no. Sex Age, y Vaccination
status Municipality ELISA
Real-time PCR (Ct)
IgG† IgM‡ VACV Parapoxvirus
1 2014030600020 F 13 Unvaccinated Valparaíso Pos (0.176) Pos (0.408) Pos (21.8) Neg
2 2014030600021 F 15 Unvaccinated Valparaíso Pos (0.393) Pos (0.450) Pos (27.8) Neg
3 2014030600022 M 46 UNK Valparaíso Pos (0.327) Pos (1.102) Inc Inc
4 2014030600023 M 34 Unvaccinated Valparaíso Pos (0.166) Neg Neg Pos (36.8)
5 2014042400031
(POX0001) F 24 Unvaccinated Valparaíso Neg Neg Pos (21.6) Neg
6 2014062800100
(POX0002) M UNK UNK Solita Neg Neg Neg Pos (35.9)
7 2013050600018 M 26 Unvaccinated Valparaíso Pos (0.254) Pos (0.898) Neg Neg
8 2013050600026 M 52 UNK Valparaíso Pos (0.213) Neg Neg Neg
9 2013050600019 M 17 Unvaccinated Valparaíso Pos (0.261) Eqi (0.094) Neg Neg
10 2013050600020 M 20 Unvaccinated Valparaíso Pos (0.384) Neg Neg Neg
11 2013050600021 M 47 UNK Valparaíso Pos (0.383) Pos (0.632) Neg Neg
12 2013050600022 M 18 Unvaccinated Valparaíso Pos (0.450) Pos (0.202) Neg Neg
13 2013050600027 M 27 Unvaccinated Valparaíso Pos (0.224) Pos (0.243) Neg Neg
14 2013050600023 M 24 Unvaccinated Valparaíso Pos (0.482) Neg Neg Neg
15 2013050600024 F 12 Unvaccinated Valparaíso Pos (0.272) Pos (0.128) Neg Neg
16 2013050600028 M 13 Unvaccinated Valparaíso Pos (0.451) Pos (0.427) Neg Neg
17 2013050600025 M 23 Unvaccinated Valparaíso Pos (1.651) Eqi (0.029) Neg Neg

*Ct, cycle threshold; eqi, equivocal; inc, inconclusive; neg, negative; pos, positive; UNK, unknown.
†OPXV IgG ELISA titers correspond to a 1:100 dilution of the serum sample.
‡OPXV IgM ELISA titers correspond to a 1:50 dilution of the serum sample.

Main Article

TOP