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Volume 23, Number 5—May 2017

Research

Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection

Matthew H. CollinsComments to Author , Eileen McGowan, Ramesh Jadi, Ellen Young, Cesar A. Lopez, Ralph S. Baric, Helen M. Lazear, and Aravinda M. de SilvaComments to Author 
Author affiliations: University of North Carolina, Chapel Hill, North Carolina, USA

Main Article

Figure 2

Schematic of the method used for depletion of human serum with DENV antigen to distinguish Zika virus–specific from cross-reactive flavivirus antibodies. Serum was incubated with DENV-1 and DENV-2 coated on polystyrene beads, enabling removal of DENV-specific and cross-reactive antibodies. DENV, dengue virus.

Figure 2. Schematic of the method used for depletion of human serum with DENV antigen to distinguish Zika virus–specific from cross-reactive flavivirus antibodies. Serum was incubated with DENV-1 and DENV-2 coated on polystyrene beads, enabling removal of DENV-specific and cross-reactive antibodies. DENV, dengue virus.

Main Article

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