Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 23, Number 8—August 2017

Research

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

Andrew D. HaddowComments to Author , Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo F. Palacios, Sina Bavari, M. Louise Pitt, and Farooq Nasar
Author affiliations: United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA

Main Article

Figure 1

Viremia and virus RNA detected in serum of rhesus and cynomolgus macaques after intravaginal inoculation with Zika virus. A) Rhesus macaques (animals R2 and R3 showed negative results); B) cynomolgus macaques (animals C1 and C2 showed negative results). Solid lines indicate virus titers in log10 PFU/mL. Dotted lines indicate genome copies in log10 copies/mL. The lower limit of detection was 1.0 log10 PFU/mL for virus titers and 3.0 log10 copies/mL for genome copies. C, cynomolgus; DPI, days post

Figure 1. Viremia and virus RNA detected in serum of rhesus and cynomolgus macaques after intravaginal inoculation with Zika virus. A) Rhesus macaques (animals R2 and R3 showed negative results); B) cynomolgus macaques (animals C1 and C2 showed negative results). Solid lines indicate virus titers in log10 PFU/mL. Dotted lines indicate genome copies in log10 copies/mL. The lower limit of detection was 1.0 log10 PFU/mL for virus titers and 3.0 log10 copies/mL for genome copies. C, cynomolgus; DPI, days postinoculation; R, rhesus.

Main Article

TOP