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CDC EID journal Volume 23 Number 8—August 2017 Main Article

Volume 23, Number 8—August 2017

Research

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

Andrew D. HaddowComments to Author , Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo Palacios, Sina Bavari, M. Louise Pitt, and Farooq Nasar
Author affiliations: United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA

Main Article

Figure 2

Viremia and virus RNA detected in serum of rhesus and cynomolgus macaques after intrarectal inoculation of Zika virus. A) Rhesus macaques (animal R6 showed negative results); B) cynomolgus macaques. Solid lines indicate virus titers in log10 PFU/mL. Dotted lines indicate genome copies in log10 copies/mL. The lower limit of detection was 1.0 log10 PFU/mL for virus titers and 3.0 log10 copies/mL for genome copies. C, cynomolgus; DPI, days postinoculation; R, rhesus.

Figure 2. Viremia and virus RNA detected in serum of rhesus and cynomolgus macaques after intrarectal inoculation of Zika virus. A) Rhesus macaques (animal R6 showed negative results); B) cynomolgus macaques. Solid lines indicate virus titers in log10 PFU/mL. Dotted lines indicate genome copies in log10 copies/mL. The lower limit of detection was 1.0 log10 PFU/mL for virus titers and 3.0 log10 copies/mL for genome copies. C, cynomolgus; DPI, days postinoculation; R, rhesus.

Main Article

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