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Volume 23, Number 8—August 2017

Research

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

Andrew D. HaddowComments to Author , Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo F. Palacios, Sina Bavari, M. Louise Pitt, and Farooq Nasar
Author affiliations: United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA

Main Article

Figure 2

Viremia and virus RNA detected in serum of rhesus and cynomolgus macaques after intrarectal inoculation of Zika virus. A) Rhesus macaques (animal R6 showed negative results); B) cynomolgus macaques. Solid lines indicate virus titers in log10 PFU/mL. Dotted lines indicate genome copies in log10 copies/mL. The lower limit of detection was 1.0 log10 PFU/mL for virus titers and 3.0 log10 copies/mL for genome copies. C, cynomolgus; DPI, days postinoculation; R, rhesus.

Figure 2. Viremia and virus RNA detected in serum of rhesus and cynomolgus macaques after intrarectal inoculation of Zika virus. A) Rhesus macaques (animal R6 showed negative results); B) cynomolgus macaques. Solid lines indicate virus titers in log10 PFU/mL. Dotted lines indicate genome copies in log10 copies/mL. The lower limit of detection was 1.0 log10 PFU/mL for virus titers and 3.0 log10 copies/mL for genome copies. C, cynomolgus; DPI, days postinoculation; R, rhesus.

Main Article

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