Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 23, Number 8—August 2017


High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

Andrew D. HaddowComments to Author , Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo Palacios, Sina Bavari, M. Louise Pitt, and Farooq Nasar
Author affiliations: United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA

Main Article

Table 1

Serologic responses of 8 female rhesus and cynomolgus macaques after intravaginal inoculation of Zika virus*

Macaque Serologic response, PRNT80, by DPI
7 15 21 28
Rhesus 1 1:640 1:640 1:640
Rhesus 2
Rhesus 3
Rhesus 4 1:640 1:640 1:640
Cynomolgus 1
Cynomolgus 2
Cynomolgus 3 1:640 1:640 1:640
Cynomolgus 4 1:1,280 1:1,280 1:1,280

*Values are titers. Limit of detection was a titer of 1:20. DPI, day postinoculation; PRNT80, 80% plaque reduction neutralization test; –, no detectable serologic response.

Main Article