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Volume 23, Number 8—August 2017

Research

High Infection Rates for Adult Macaques after Intravaginal or Intrarectal Inoculation with Zika Virus

Andrew D. HaddowComments to Author , Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo F. Palacios, Sina Bavari, M. Louise Pitt, and Farooq Nasar
Author affiliations: United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA

Main Article

Table 1

Serologic responses of 8 female rhesus and cynomolgus macaques after intravaginal inoculation of Zika virus*

Macaque Serologic response, PRNT80, by DPI
7 15 21 28
Rhesus 1 1:640 1:640 1:640
Rhesus 2
Rhesus 3
Rhesus 4 1:640 1:640 1:640
Cynomolgus 1
Cynomolgus 2
Cynomolgus 3 1:640 1:640 1:640
Cynomolgus 4 1:1,280 1:1,280 1:1,280

*Values are titers. Limit of detection was a titer of 1:20. DPI, day postinoculation; PRNT80, 80% plaque reduction neutralization test; –, no detectable serologic response.

Main Article

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