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Volume 24, Number 1—January 2018
Dispatch

Serologic Evidence of Fruit Bat Exposure to Filoviruses, Singapore, 2011–2016

Eric D. Laing1, Ian H. Mendenhall1, Martin Linster, Dolyce H. W. Low, Yihui Chen, Lianying Yan, Spencer L. Sterling, Sophie Borthwick, Erica Sena Neves, Julia S. L. Lim, Maggie Skiles, Benjamin P. Y.-H. Lee, Lin-Fa Wang, Christopher C. Broder, and Gavin J. D. SmithComments to Author 
Author affiliations: Uniformed Services University, Bethesda, Maryland, USA (E.D. Laing, L. Yan, S.L. Sterling, C.C. Broder); Duke-National University of Singapore Medical School, Singapore, Singapore (I.H. Mendenhall, M. Linster, D.H.W. Low, Y. Chen, S. Borthwick, E.S. Neves, J.S.L. Lim, L.-F. Wang, G.J.D. Smith); North Carolina State University, Raleigh, North Carolina, USA (M. Skiles); National Parks Board, Singapore (B.P.Y.-H. Lee); Duke University, Durham, North Carolina, USA (L.-F. Wang, G.J.D. Smith)

Main Article

Table 2

Bio-Plex median fluorescence intensity values for bat serum positive for >1 filovirus antigen*

Bat species, ID EBOV BDBV TAFV SUDV RESTVm RESTVp MARV(Mus) MARV(Ang) RAVV
Eonycteris spelaea, n = 186
0805149† 738 124 68 40 44 22 23 21 24
080814 86 318 105 258 26 12 17 16 20
082154 143 161 113 214 35 41 21 31 39
052313 284 408 177 285 89 72 29 23 30
052335 203 191 124 219 42 21 38 38 24
052339 357 306 141 293 54 31 26 26 42
071839 330 299 164 480 65 44 28 33 45
071842 446 327 202 362 65 49 42 38 57
110733 126 416 166 95 58 42 34 42 58
011603† 1151 130 91 69 36 32 51 35 39
011616 252 294 168 175 32 49 47 29 50
011656 306 386 204 394 89 73 18 39 37
012309† 579 659 315 69 35 31 27 33 35
021303 478 431 188 450 52 37 24 30 47
111903 469 384 276 113 52 57 37 69 54
111907 285 336 213 158 39 36 29 50 30
042722
260
262
174
167
75
31
54
24
42
Cynopterus brachyotis, n = 153
051253 121 133 59 242 40 41 19 25 68
0516613 146 293 127 73 47 36 25 29 22
0516632 138 139 86 356 35 25 28 34 34
0726122† 119 501 100 60 40 46 25 19 29
1103241 84 141 128 241 50 47 66 38 34
100903 148 201 71 108 42 33 18 16 36
100914 74 228 70 55 39 38 30 27 26
100925 166 304 109 116 43 18 33 30 28
021357 201 299 179 264 65 44 25 55 47
050804 242 276 140 124 41 30 34 33 44
050818 383 374 198 332 60 55 29 26 68
040807† 297 597 194 192 40 38 122 95 32
042701†
339
547
222
417
60
78
54
25
62
Penthetor lucasi, n = 70
062590† 34 496 93 39 36 18 23 17 23
070409† 95 238 129 89 62 27 34 36 37
112112† 251 352 148 235 51 29 23 23 29

*Bio-Plex manufactured by Bio-Rad (Hercules, CA, USA). Boldface indicates positive results. BDBV, Bundibugyo virus; EBOV, Ebola virus; ID, specimen identification number; MARV(Mus), Marburg virus–Musoke; MARV(Ang), Marburg virus–Angola; RESTVm, Reston virus–monkey; RESTVp, Reston virus–pig; SUDV, Sudan virus; RAVV, Ravn virus; TAFV, Taï Forest virus.
†Sample screened by Western blot and shown in Figure 2.

Main Article

1These authors contributed equally to this article.

Page created: December 19, 2017
Page updated: December 19, 2017
Page reviewed: December 19, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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