New Parvovirus Associated with Serum Hepatitis in Horses after Inoculation of Common Biological Product
Thomas J. Divers, Bud C. Tennant
1, Arvind Kumar, Sean McDonough, John Cullen, Nishit Bhuva, Komal Jain, Lokendra Singh Chauhan, Troels Kasper Høyer Scheel, W. Ian Lipkin, Melissa Laverack, Sheetal Trivedi, Satyapramod Srinivasa, Laurie Beard, Charles M. Rice, Peter D. Burbelo, Randall W. Renshaw, Edward Dubovi, and Amit Kapoor
Author affiliations: Cornell University, Ithaca, New York, USA (T.J. Divers, B.C. Tennant, S. McDonough, M. Laverack, R.W. Renshaw, E. Dubovi); Nationwide Children’s Hospital, Columbus, Ohio, USA (A. Kumar, S. Trivedi, S. Srinivasa, A. Kapoor); North Carolina State University, Raleigh, North Carolina, USA (J. Cullen); Columbia University, New York, New York, USA (N. Bhuva, K. Jain, L.S. Chauhan, W.I. Lipkin); University of Copenhagen, Copenhagen, Denmark (T.K.H. Scheel); Hvidovre Hospital, Copenhagen (T.K.H. Scheel); Rockefeller University, New York (T.K.H. Scheel, C.M. Rice); Kansas State University, Manhattan, Kansas, USA (L. Beard); National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA (P.D. Burbelo)
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Figure 3
Figure 3. Kinetics of viremia and liver enzymes and time of seroconversion in 2 horses experimentally inoculated with equine parvovirus hepatitis. Gray line indicates horse 1; black line indicates horse 2. A) AST; B) SDH; C) GGT; D) total bilirubin; E) bile acids; F) DNA copies. Asterisk indicates time of seroconversion. AST, aspartate aminotransferase; GGT, γ-glutamyltransferase. SDH, sorbitol dehydrogenase.
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