Volume 24, Number 2—February 2018
Research
Yersinia pestis Survival and Replication in Potential Ameba Reservoir
Figure 4

Figure 4. Representative transmission electron micrographs (TEM) depict Acanthamoeba castellanii amebae during A) 10-minute, B) 30-minute, and C) 24-hour co-cultures (multiplicity of infection 100) with Yersinia pestis (CO92 pgm+, pCD1, pGFPuv, amp+). Red arrows in panel A indicate potential intraameba mitotic division of Y. pestis bacterium. Visual analysis of TEM micrographs proved inconclusive for identifying the bacterial division septum. Y. pestis resides within the potential replicative niche of a tight-fitting vacuolar membrane, similar to Yersinia-containing vacuoles observed in macrophages. YP, Y. pestis; CV, central vacuole; DV, digestive vacuole; M, mitochondria. Scale bars indicate 3 μm.
- Page created: January 17, 2018
- Page last updated: January 17, 2018
- Page last reviewed: January 17, 2018
- Centers for Disease Control and Prevention,
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National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
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