Volume 24, Number 3—March 2018
Synopsis
Coccidioidomycosis Outbreaks, United States and Worldwide, 1940–2015
Michael Freedman, Brendan R. Jackson, Orion McCotter, and Kaitlin Benedict
Table 2
Characteristics of patients with coccidioidomycosis outbreak–associated cases, United States and worldwide, 1940–2015
| Patient characteristic | Time period, no. (%) cases | |||
|---|---|---|---|---|
| 1940–1959 |
1960–1979 |
1980–2015 |
Total 1940–2015 |
|
| Presentation and diagnosis | ||||
| Total | 503 (100) | 482 (100) | 479 (100) | 1,464 (100) |
| Symptomatic | 493 (98) | 481 (100) | 477 (100) | 1,451 (99) |
| Any positive studies | 290 (58) | 466 (97) | 242 (51) | 998 (68) |
| Positive serology | 156 (31) | 68 (14) | 110 (23) | 334 (23) |
| Positive skin test result | 270 (54) | 82 (17) | 26 (5) | 378 (26) |
| Positive culture | 15 (3) | 2 (<1) | 13 (3) | 30 (2) |
| Positive chest radiograph |
50 (10) |
67 (14) |
36 (8) |
153 (10) |
| Clinical outcome | ||||
| Total* | 475 (100) | 472 (100) | 320 (100) | 1,267 (100) |
| Hospitalized | 430 (91) | 20 (4) | 94 (29) | 544 (43) |
| Dissemination | 7 (1) | 16 (3) | 9 (3) | 32 (3) |
| Meningitis | 3 (1) | 15 (3) | 2 (1) | 20 (2) |
| Deaths | 5 (1) | 8 (2) | 5 (2) | 18 (1) |
| Treated with antifungal drugs† | 0 | 5 (1) | 123 (44) | 128 (18) |
*Cases among outbreaks reporting health outcomes.
†Of 717 cases among 20 outbreaks documenting antifungal drug treatment.
Page created: February 15, 2018
Page updated: February 15, 2018
Page reviewed: February 15, 2018
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