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Volume 24, Number 4—April 2018
Dispatch

mcr-1 in Carbapenemase-Producing Klebsiella pneumoniae with Hospitalized Patients, Portugal, 2016–2017

Ana Constança Mendes1, Ângela Novais1, Joana Campos, Carla Rodrigues, Cláudia Santos, Patrícia Antunes, Helena Ramos, and Luísa PeixeComments to Author 
Author affiliations: Centro Hospitalar do Porto, Porto, Portugal (A.C. Mendes, C. Santos, H. Ramos); Faculdade de Farmácia, Universidade do Porto, Porto (Â. Novais, J. Campos, C. Rodrigues, P. Antunes, L. Peixe); Faculdade de Ciências da Nutrição e Alimentação, Universidade do Porto, Porto (P. Antunes)

Main Article

Figure 2

Alignment of representative mcr-1–harboring IncX4 plasmids from different isolation sources and geographic regions. The mcr-1–harboring plasmid pAN_M1A was used as a reference plasmid. The outermost circle is an annotation of the reference plasmid and shows the direction of transcriptional open-reading frames. The pil loci and other genes (gray), replication-associated genes (dark blue), antimicrobial drug resistance gene (red), and insertion sequence (green) are indicated. The strategy for PCR

Figure 2. Alignment of representative mcr-1–harboring IncX4 plasmids from different isolation sources and geographic regions. The mcr-1–harboring plasmid pAN_M1A was used as a reference plasmid. The outermost circle is an annotation of the reference plasmid and shows the direction of transcriptional open-reading frames. The pil loci and other genes (gray), replication-associated genes (dark blue), antimicrobial drug resistance gene (red), and insertion sequence (green) are indicated. The strategy for PCR mapping of mcr-1–carrying plasmids is indicated by red arrows. Primer P1 targets pirF, P2 mcr-1 (3.3 kb), P3 mcr-1, and P4 parA (2.1 kb).

Main Article

1These authors contributed equally to this article.

Page created: March 19, 2018
Page updated: March 19, 2018
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