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Volume 24, Number 6—June 2018
Research

Genomic Epidemiology of Global Carbapenemase-Producing Enterobacter spp., 2008–2014

Gisele Peirano1, Yasufumi Matsumura1, Mark D. Adams2, Patricia Bradford, Mary Motyl, Liang Chen, Barry N. Kreiswirth, and Johann D.D. PitoutComments to Author 
Author affiliations: University of Calgary, Calgary, Alberta, Canada (G. Peirano, J.D.D. Pitout); Kyoto University Graduate School of Medicine, Kyoto, Japan (Y. Matsumura); J. Craig Venter Institute, La Jolla, California, USA (M.D. Adams); AstraZeneca Pharmaceuticals LP, Waltham, Massachusetts, USA (P. Bradford); Merck & Co., Inc., Rahway, New Jersey, USA (M. Motyl); Rutgers University, Newark, New Jersey, USA (L. Chen, B.N. Kreiswirth); University of Pretoria, Pretoria, South Africa (J.D.D. Pitout)

Main Article

Figure 1

Phylogenetic tree of the different species and sequence types among 160 Enterobacter cloacae complex isolates identified from Enterobacter spp. isolates collected in the Merck Study for Monitoring Antimicrobial Resistance Trends, 2008–2014, and the AstraZeneca global surveillance program, 2012–2014. The tree is rooted with E. cloacae complex Hoffmann cluster IX (Chavda group R) strain 35,699. A total of 369,123 core single-nucleotide polymorphisms were found; 4,010 were used to draw the tree (af

Figure 1. Phylogenetic tree of the different species and sequence types among 160 Enterobacter cloacae complex isolates identified from Enterobacter spp. isolates collected in the Merck Study for Monitoring Antimicrobial Resistance Trends, 2008–2014, and the AstraZeneca global surveillance program, 2012–2014. The tree is rooted with E. cloacae complex Hoffmann cluster IX (Chavda group R) strain 35,699. A total of 369,123 core single-nucleotide polymorphisms were found; 4,010 were used to draw the tree (after phages and recombination sites were excluded). KPC, Klebsiella pneumoniae carbapenemase; NDM, New Delhi metallo-β-lactamase; OXA, oxacillin; ST, sequence type; –, information missing; *, isolate identified in another study. Scale bar indicates nucleotide substitutions per site.

Main Article

1These co-authors contributed equally to this article.

2Current affiliation: Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.

Page created: May 17, 2018
Page updated: May 17, 2018
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