Volume 25, Number 1—January 2019
Research
Effects of Antibiotic Cycling Policy on Incidence of Healthcare-Associated MRSA and Clostridioides difficile Infection in Secondary Healthcare Settings
Table 3
Segmented regression analysis of effect of stopping cycling on the incidence of HA-CDI, HA-MRSA, and new ESBL isolates in Antrim Area Hospital, Northern Ireland, UK*
Variable | Coefficient | 95% CI | SE | p value |
---|---|---|---|---|
HA-CDI | ||||
Constant | 0.0173 | 0.0062 to 0.0284 | 0.0054 | <0.01 |
Trend | 4.73 × 10−4 | −0.0003 to 0.0012 | 0.0004 | 0.22 |
Change | ||||
In level | −0.0159 | −0.0352 to 0.0033 | 0.0094 | 0.10 |
In trend |
0.0005 |
−0.0018 to 0.0028 |
0.0011 |
0.65 |
HA-MRSA | ||||
Constant | 0.0598 | 0.0388 to 0.0810 | 0.0102 | <0.01 |
Trend | 0.0012 | −0.0002 to 0.0027 | 0.0007 | 0.10 |
Change | ||||
In level | −0.0350 | −0.0711 to −0.001 | 0.0179 | 0.06 |
In trend |
−0.0016 |
−0.002 to 0.0027 |
0.0022 |
0.45 |
New ESBL | ||||
Constant | 0.0438 | 0.0200 to 0.0672 | 0.0115 | <0.01 |
Trend | 0.0005 | −0.0011 to 0.0021 | 0.0008 | 0.56 |
Change | ||||
In level | 0.0419 | 0.0017 to 0.0820 | 0.0199 | 0.04 |
In trend | −0.0026 | −0.0074 to 0.0023 | 0.0024 | 0.30 |
*In this hospital, a cycling policy was in place during October 2013–September 2015, and a standard policy was in place during October 2015–September 2016. Bold indicates statistical significance. ESBL, extended-spectrum β-lactamase; HA-CDI, healthcare-associated Clostridioides difficile infection; HA-MRSA, healthcare-associated methicillin-resistant Staphylococcus aureus.
1Current affiliation: Craigavon Area Hospital, Craigavon, Northern Ireland, UK.
Page created: December 17, 2018
Page updated: December 17, 2018
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