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Volume 25, Number 6—June 2019

Nontuberculous Mycobacterial Musculoskeletal Infection Cases from a Tertiary Referral Center, Colorado, USA

Noah Goldstein1, J. Benjamin St. Clair1, Shannon H. Kasperbauer, Charles L. Daley, and Bennie LindequeComments to Author 
Author affiliations: University of Colorado, Aurora, Colorado, USA (N. Goldstein, J.B. St. Clair, S.H. Kasperbauer, B. Lindeque); University of Chicago, Chicago, Illinois, USA (J.B. St. Clair); National Jewish Health, Denver, Colorado, USA (S.H. Kasperbauer, C.L. Daley)

Main Article

Table 1

Demographics of patients in retrospective study of nontuberculous mycobacterial musculoskeletal infections, Colorado, USA*

Patient no. Age, y/sex Immunocompromising conditions Inciting or predisposing factor(s) Time to symptom onset, mo Reason care sought Time from symptom onset to diagnosis, mo Diagnostic procedure, source of microbiologic diagnosis
1 55/M History of lymphoma, pseudogout, oral steroid use Steroid injection, left ankle UNK Osteomyelitis, septic arthritis 12 Tissue sample from ankle debridement
2 53/F None Pedicure 0 Synovitis, osteomyelitis, cellulitis 4 UNK; diagnosis at another hospital
3 48/F None Second THA UNK PJI UNK Thigh fluid sampled during I&D
4 45/M None AKA 1 Draining wound at stump 2 Sample of fluid draining from AKA stump
5 64/F None Carpal tunnel release 0 Tenosynovitis, septic arthritis 8 Synovial fluid obtained during excision of synovitis
6 69/F Diabetes mellitus THA 6 PJI 9 Synovial biopsy obtained during explantation
7 23/F Systemic lupus erythematosus, oral steroids, hydroxyl-chloroquine, mycophenolate mofetil Avascular necrosis, ankle fusion 3 Septic arthritis, osteomyelitis, skin abscesses 1 UNK; diagnosis at another hospital
8 57/F Polymyositis, oral steroids, azathioprine, rituximab, methotrexate ACL repair, arthroscopy, steroid injection UNK Septic arthritis UNK Aspirate of left knee and right hip
9 76/M Nonspecific autoimmune disease, oral steroids Calcium pyrophosphate deposition disease, TKA 0 PJI 2 UNK; diagnosis at another hospital
10 58/M None Trauma, steroid injection 12 Septic arthritis 19 UNK; diagnosis at another hospital
11 77/F Rheumatoid arthritis, prednisone, azathioprine TKA 300 PJI 12 Synovial biopsy obtained during placement of antimicrobial spacer
12 83/M Malnutrition, prednisone TKA 168 PJI 8 Tissue obtained during TKA revision
13 49/F None TKA (revision) 14 PJI 2 UNK; diagnosis at another hospital
14 24/F Crohn’s disease, infliximab Failed IV 0 Cellulitis, abscess 7 Skin biopsy

*AKA, above-knee amputation; I&D, irrigation and debridement; PJI, prosthetic joint infection, THA, total hip arthroplasty; TKA, total knee arthroplasty; UNK, unknown.

Main Article

1These first authors contributed equally to this article.

Page created: May 24, 2019
Page updated: May 24, 2019
Page reviewed: May 24, 2019
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