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Volume 25, Number 6—June 2019
CME ACTIVITY - Synopsis

Nontuberculous Mycobacterial Musculoskeletal Infection Cases from a Tertiary Referral Center, Colorado, USA

Noah Goldstein1, J. Benjamin St. Clair1, Shannon H. Kasperbauer, Charles L. Daley, and Bennie LindequeComments to Author 
Author affiliations: University of Colorado, Aurora, Colorado, USA (N. Goldstein, J.B. St. Clair, S.H. Kasperbauer, B. Lindeque); University of Chicago, Chicago, Illinois, USA (J.B. St. Clair); National Jewish Health, Denver, Colorado, USA (S.H. Kasperbauer, C.L. Daley)

Main Article

Table 1

Demographics of patients in retrospective study of nontuberculous mycobacterial musculoskeletal infections, Colorado, USA*

Patient no. Age, y/sex Immunocompromising conditions Inciting or predisposing factor(s) Time to symptom onset, mo Reason care sought Time from symptom onset to diagnosis, mo Diagnostic procedure, source of microbiologic diagnosis
1 55/M History of lymphoma, pseudogout, oral steroid use Steroid injection, left ankle UNK Osteomyelitis, septic arthritis 12 Tissue sample from ankle debridement
2 53/F None Pedicure 0 Synovitis, osteomyelitis, cellulitis 4 UNK; diagnosis at another hospital
3 48/F None Second THA UNK PJI UNK Thigh fluid sampled during I&D
4 45/M None AKA 1 Draining wound at stump 2 Sample of fluid draining from AKA stump
5 64/F None Carpal tunnel release 0 Tenosynovitis, septic arthritis 8 Synovial fluid obtained during excision of synovitis
6 69/F Diabetes mellitus THA 6 PJI 9 Synovial biopsy obtained during explantation
7 23/F Systemic lupus erythematosus, oral steroids, hydroxyl-chloroquine, mycophenolate mofetil Avascular necrosis, ankle fusion 3 Septic arthritis, osteomyelitis, skin abscesses 1 UNK; diagnosis at another hospital
8 57/F Polymyositis, oral steroids, azathioprine, rituximab, methotrexate ACL repair, arthroscopy, steroid injection UNK Septic arthritis UNK Aspirate of left knee and right hip
9 76/M Nonspecific autoimmune disease, oral steroids Calcium pyrophosphate deposition disease, TKA 0 PJI 2 UNK; diagnosis at another hospital
10 58/M None Trauma, steroid injection 12 Septic arthritis 19 UNK; diagnosis at another hospital
11 77/F Rheumatoid arthritis, prednisone, azathioprine TKA 300 PJI 12 Synovial biopsy obtained during placement of antimicrobial spacer
12 83/M Malnutrition, prednisone TKA 168 PJI 8 Tissue obtained during TKA revision
13 49/F None TKA (revision) 14 PJI 2 UNK; diagnosis at another hospital
14 24/F Crohn’s disease, infliximab Failed IV 0 Cellulitis, abscess 7 Skin biopsy

*AKA, above-knee amputation; I&D, irrigation and debridement; PJI, prosthetic joint infection, THA, total hip arthroplasty; TKA, total knee arthroplasty; UNK, unknown.

Main Article

1These first authors contributed equally to this article.

Page created: May 24, 2019
Page updated: May 24, 2019
Page reviewed: May 24, 2019
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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