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Volume 26, Number 12—December 2020
CME ACTIVITY - Research

Clinical and Multimodal Imaging Findings and Risk Factors for Ocular Involvement in a Presumed Waterborne Toxoplasmosis Outbreak, Brazil1

Camilo Brandão-de-Resende, Helena Hollanda Santos, Angel Alessio Rojas Lagos, Camila Munayert Lara, Jacqueline Souza Dutra Arruda, Ana Paula Maia Peixoto Marino, Lis Ribeiro do Valle Antonelli, Ricardo Tostes Gazzinelli, Ricardo Wagner de Almeida Vitor, and Daniel Vitor Vasconcelos-SantosComments to Author 
Author affiliations: Universidade Federal de Minas Gerais, Belo Horizonte, Brazil (C. Brandão-de-Resende, H.H. Santos, A.A.R. Lagos, C.M. Lara, J.S.D. Arruda, R.W.A, Vitor, D.V. Vasconcelos-Santos); Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte (A.P.M.P. Marino, L.R.V. Antonelli, R.T. Gazzinelli).

Main Article

Figure 2

A large necrotizing retinochoroiditis lesion in the right eye, detected in baseline examination (VA 0.5) of a 42-year-old man in a presumed waterborne toxoplasmosis outbreak, Brazil. A) Fundus photograph showing dense focal retinal whitening with indistinct borders, associated with overlying vitreous haze. B) Fundus fluorescein angiography; green arrow indicates hyperfluorescence of optic disc. C) Fundus fluorescein angiography; yellow arrows indicate hyperfluorescence indicating late leakage at the margins of the retinochoroiditis lesion. D) Red-free reflectance showing changes at the level of the active lesion. Green line indicates site of optical coherence tomography scan. E) Spectral-domain optical coherence tomography; blue arrows indicate focal full-thickness hyper-reflectivity and disorganization of retinal layers, surrounding retinal thickening, and numerous overlying hyper-reflective dots and bands, indicating exuberant inflammatory vitreous exudation. Scale bars indicate 200 µm. VA, visual acuity.

Figure 2. A large necrotizing retinochoroiditis lesion in the right eye, detected in baseline examination (VA 0.5) of a 42-year-old man in a presumed waterborne toxoplasmosis outbreak, Brazil. A) Fundus photograph showing dense focal retinal whitening with indistinct borders, associated with overlying vitreous haze. B) Fundus fluorescein angiography; green arrow indicates hyperfluorescence of optic disc. C) Fundus fluorescein angiography; yellow arrows indicate hyperfluorescence indicating late leakage at the margins of the retinochoroiditis lesion. D) Red-free reflectance showing changes at the level of the active lesion. Green line indicates site of optical coherence tomography scan. E) Spectral-domain optical coherence tomography; blue arrows indicate focal full-thickness hyper-reflectivity and disorganization of retinal layers, surrounding retinal thickening, and numerous overlying hyper-reflective dots and bands, indicating exuberant inflammatory vitreous exudation. Scale bars indicate 200 µm. VA, visual acuity.

Main Article

1Presented in part at the 2015 American Uveitis Society Fall meeting, November 15, 2014, Las Vegas, Nevada, USA

Page created: October 05, 2020
Page updated: November 19, 2020
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