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Volume 26, Number 8—August 2020
Research

Increased Sensitivity of Plasmodium falciparum to Artesunate/Amodiaquine Despite 14 Years as First-Line Malaria Treatment, Zanzibar

Mwinyi Msellem, Ulrika Morris, Aungpaing Soe, Faiza B. Abbas, Abdul-Wahid Ali, Rory Barnes, Paolo Frumento, Abdullah S. Ali, Andreas Mårtensson, and Anders BjörkmanComments to Author 
Author affiliations: Mnazi Mmoja Hospital, Zanzibar, Tanzania (M. Msellem); Karolinska Institutet, Stockholm, Sweden (U. Morris, A. Soe, R. Barnes, P. Frumento, A. Bjorkman); Zanzibar Malaria Elimination Programme, Zanzibar, Tanzania (F.B. Abbas, A.-W. Ali, A.S. Ali); Uppsala University, Uppsala, Sweden (A. Mårtensson)

Main Article

Table 2

Characteristics of patients fulfilling study protocol in 2017, by age group and parasite density, Zanzibar

Characteristic Study group
2017, all patients 2017, children <5 y of age 2017, children <10 y of age 2017, children <15 y of age 2017, parasite density >2,000/μL
Total 142 21 42 66 115
M:F ratio 99:43 13:8 28:14 45:21 81:34
Median age (range) 17 (2–60) y 48 (21–60) mo 5.5 (1.8–10) y 9 (1.8–15) y 16 (1.8–60) y
Geometric mean parasite density/μL (range) 7,899 
(75–304,000) 15,773 
(85–304,000) 11,847 
(85–304,000) 10,618 
(85–304,000) 14,305 
(2,175–304,000)
Mean ± SD temperature, °C 37.8 ± 1.4 38.2 ± 1.2 38.1 ± 1.1 38.2 ± 1.2 37.9 ± 1.4
Mean ± SD hemoglobin level, g/dL 11.9 ± 2.2 9.1 ± 1.7 9.8 ± 1.9 10.6 ± 2.1 11.8 ± 2.3

Main Article

Page created: May 26, 2020
Page updated: July 17, 2020
Page reviewed: July 17, 2020
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