Volume 27, Number 1—January 2021
Research
Intrafamilial Exposure to SARS-CoV-2 Associated with Cellular Immune Response without Seroconversion, France
Figure 4
![Correlation of the T-cell responses against spike glycoprotein antigens of SARS-CoV-2 and HCoVs 229E and OC43 in study of intrafamilial exposure to SARS-CoV-2, France. Means of spot counts of interferon gamma–producing T cells per 1 million CD3+ cells in response to peptide pools spanning the N terminal (S1) and the C-terminal (S2) regions of spike glycoproteins of SARS-CoV-2 compared with HCoV-229E (A) and HCoV-OC43 (B) in 11 confirmed coronavirus disease cases (index patients), their seronegative partners (contacts), and 10 healthy blood donor controls. HCoV, human coronavirus; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.](/eid/images/20-3611-F4.jpg)
Figure 4. Correlation of the T-cell responses against spike glycoprotein antigens of SARS-CoV-2 and HCoVs 229E and OC43 in study of intrafamilial exposure to SARS-CoV-2, France. Means of spot counts of interferon gamma–producing T cells per 1 million CD3+ cells in response to peptide pools spanning the N terminal (S1) and the C-terminal (S2) regions of spike glycoproteins of SARS-CoV-2 compared with HCoV-229E (A) and HCoV-OC43 (B) in 11 confirmed coronavirus disease cases (index patients), their seronegative partners (contacts), and 10 healthy blood donor controls. HCoV, human coronavirus; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
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