Volume 27, Number 1—January 2021
Research
Intrafamilial Exposure to SARS-CoV-2 Associated with Cellular Immune Response without Seroconversion, France
Table 1
Clinical and virological characteristics of COVID-19 patients and their contacts at symptom onset, Strasbourg, France, March 10–26, 2020*
| ID | Age, y/sex | RT-PCR† | Duration of symptoms, d | Symptom onset delay, d‡ | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms |
||||||||||||
| Fever | Cough | Fatigue | Headache | Anosmia | Agueusia | Dyspnea | Myalgia | |||||
| Couples with symptomatic contacts | ||||||||||||
| P1 | 47/F | ND | Y | N | Y | Y | Y | Y | N | Y | 15 | 5 |
| C1 |
50/M |
ND |
Y |
N |
N |
N |
N |
N |
N |
N |
3 |
|
| P2 | 54/F | ND | Y | Y | Y | Y | Y | Y | N | 13 | 7 |
|
| C2 |
57/M |
ND |
Y |
N |
Y |
Y |
N |
N |
Y |
N |
6 |
|
| P4§ | 45/M | Pos (8.39) | Y | Y | N | Y | Y | Y | N | N | 12 | 6 |
| C4 |
48/F |
Neg |
Y |
Y |
N |
Y |
N |
N |
N |
N |
10 |
|
| P5 | 38/M | Pos (7.65) | Y | N | N | Y | Y | Y | N | N | 2 | 10 |
| C5 |
40/F |
Neg |
N |
Y |
N |
Y |
N |
N |
N |
N |
7 |
|
| P7 | 45/M | Pos | Y | Y | N | N | Y | Y | N | Y | 4 | 1 |
| C7 |
45/F |
Neg |
N |
N |
N |
N |
N |
Y |
N |
N |
1 |
|
| P8 | 63/M | Pos | Y | N | Y | Y | Y | Y | N | N | 10 | 10 |
| C8 |
57/F |
ND |
N |
N |
Y |
N |
N |
N |
N |
Y |
10 |
|
| Couples with asymptomatic contacts |
||||||||||||
| P3 | 65/F | ND | N | Y | N | Y | N | N | N | N | 9 | NA |
| C3 |
61/M |
ND |
Asymptomatic |
NA |
||||||||
| P6# | 43/F | Pos (3.99) | N | Y | N | N | Y | Y | Y | N | 7 | NA |
| C6 |
45/M |
ND |
Asymptomatic |
NA |
||||||||
| P9 | 57/M | Pos (6.20) | Y | Y | N | N | N | N | Y | Y | 14 | NA |
| C9 |
58/F |
ND |
Asymptomatic |
NA |
||||||||
| P10 | 39/F | Neg | N | N | N | Y | Y | Y | N | N | 10 | NA |
| C10 |
39/M |
ND |
Asymptomatic |
NA |
||||||||
| P11 | 58/F | Pos (8.46) | Y | N | Y | Y | N | N | N | N | 21 | NA |
| C11 | 57/M | ND | Asymptomatic |
NA | ||||||||
*In ID column, same number indicates partners in 1 couple. C, contact; d, days; ID, identification; ND, not done; NA, not applicable; neg, negative; P, index patient; pos, positive; RT-PCR, reverse-transcription PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2. †SARS-CoV-2 RT-PCR was performed in nasopharyngeal specimens during the symptomatic phase. When available, viral load (log copies/reaction) is indicated in parentheses below the result. ‡Days from symptom onset in index patient to onset in contact. §This index patient quarantined himself by dining separately and wearing a mask after positive SARS-CoV-2 PCR testing 1 day after symptom onset. #This index patient wore a mask after positive SARS-CoV-2 PCR testing 3 days after symptom onset.