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Volume 27, Number 10—October 2021

Fatal Exacerbations of Systemic Capillary Leak Syndrome Complicating Coronavirus Disease

Patricia C. Cheung, A. Robin Eisch, Noble Maleque, Derek M. Polly, Sara C. Auld, and Kirk M. DrueyComments to Author 
Author affiliations: Emory University School of Medicine and Rollins School of Public Health, Atlanta, Georgia, USA (P.C. Cheung, N. Maleque, S.C. Auld); National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, Maryland, USA (A.R. Eisch, K.M. Druey); Emory University Hospital Midtown Department of Pharmacy, Atlanta (D.M. Polly)

Main Article

Table 3

Typical serum cytokine profiles for acute SCLS compared with severe COVID-19*

Cytokine SCLS COVID-19
IL-2 Normal Elevated
IL-4 Normal Elevated
IL-6 Elevated Elevated
IL-7 Normal Elevated
IL-10 Normal Elevated
CXCL10 Elevated Elevated
CCL2 Elevated Elevated
TNF-α Variable Elevated
IFN-γ Elevated Elevated

*COVID-19, coronavirus disease; CCL, C-C motif chemokine ligand; CXCL, C-X-C motif chemokine ligand; IFN, interferon; IL, interleukin; SCLS, systemic capillary leak syndrome; TNF, tumor necrosis factor.

Main Article

Page created: July 15, 2021
Page updated: September 19, 2021
Page reviewed: September 19, 2021
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