Effectiveness of Preventive Therapy for Persons Exposed at Home to Drug-Resistant Tuberculosis, Karachi, Pakistan
Amyn A. Malik
, Neel R. Gandhi, Timothy L. Lash, Lisa M. Cranmer, Saad B. Omer, Junaid F. Ahmed, Sara Siddiqui, Farhana Amanullah, Aamir J. Khan, Salmaan Keshavjee, Hamidah Hussain1
, and Mercedes C. Becerra1
Author affiliations: Emory University Rollins School of Public Health, Atlanta, Georgia, USA (A.A. Malik, N.R. Gandhi, T.L. Lash); Yale University, New Haven, Connecticut, USA (A.A. Malik, S.B. Omer); Global Health Directorate, Indus Health Network, Karachi, Pakistan (A.A. Malik, J.F. Ahmed, S. Siddiqui); Interactive Research and Development, Singapore (A.A. Malik, A.J. Khan, H. Hussain); Emory University School of Medicine, Atlanta (N.R. Gandhi, L.M. Cranmer); Emory + Children’s Pediatric Institute, Atlanta (L.M. Cranmer); The Indus Hospital, Karachi (F. Amanullah); Harvard University, Cambridge, Massachusetts, USA (A.J. Khan, S. Keshavjee, M.C. Becerra); Partners In Health, Boston, Massachusetts, USA (S. Keshavjee, M.C. Becerra); Brigham and Women’s Hospital, Boston (S. Keshavjee, M.C. Becerra)
Figure 2. Risk ratios for effectiveness of preventive therapy using data from published studies and a summary measure in study of preventive therapy for persons exposed at home to drug-resistant tuberculosis, Karachi, Pakistan, February 2016–March 2017. Solid line on y axis indicates null. Dotted line indicates pooled estimate of preventive therapy effectiveness. Blue diamond indicates 95% CI. Small diamonds indicate point estimates of preventive therapy effectiveness using data from each study with its CI. RR, risk ratio.
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