Volume 27, Number 4—April 2021
Research
Evolution of Sequence Type 4821 Clonal Complex Hyperinvasive and Quinolone-Resistant Meningococci
Table 2
Specific alleles of antigenic genes in 4 sublineages of clonal complex 4821 of Neisseria meningitidis
Sublineage | Antigen allele no. (no. isolates) |
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---|---|---|---|---|---|---|---|---|---|
PorA | fHbp | nhba | PorB | FetA-VR | opcA | nspA | tbpA | NMB-0315 | |
L44.1, n = 50 | P1.7–2,14 (25) | 22 (12) | 124 (48) | 3–48 (47) | F3–3 (45) | None | 4 (49) | 7 (36) | None |
P1.12–1,16–8 (9) | 489 (13) | ||||||||
498 (15) |
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L44.2, n = 29 | None | None | 965 (10) | 3–81 (15) | F1–91 (20) | None | None | None | 335 (26) |
967 (12) |
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L44.3, n = 58 | P1.17–6,23-x* (23) | None | None | 3–229 (35) | F3–9 (8) | 100 (40) | 26 (39) | 1,333 (31) | 194 (49) |
F3–36 (37) |
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L44.4, n = 32 | P1.5–3,10–2 (8) | None | None | 3–460 (7) | F1–7 (11) | None | 117 (20) | None | None |
*23-x refers to 23, 23–2, and 23–6.
1These authors contributed equally to this article.
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