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Volume 27, Number 4—April 2021
Research

Epidemiologic and Genomic Reidentification of Yaws, Liberia

Joseph W.S. TimothyComments to Author , Mathew A. Beale, Emerson Rogers, Zeela Zaizay, Katherine E. Halliday, Tarnue Mulbah, Romeo K. Giddings, Stephen L. Walker, Nicholas R. Thomson, Karsor K. Kollie1, Rachel L. Pullan1, and Michael Marks1
Author affiliations: London School of Hygiene and Tropical Medicine, London, UK (J.W.S. Timothy, K.E. Halliday, S.L. Walker, N.R. Thomson, R.L. Pullan, M. Marks); Wellcome Sanger Institute, Hinxton, UK (M.A. Beale, N.R. Thomson); Ministry of Health, Monrovia, Liberia (E. Rogers, Z. Zaizay, T. Mulbah, R.K. Giddings, K.K. Kollie); University College London Hospitals NHS Foundation Trust, London (S.L. Walker, M. Marks)

Main Article

Figure 1

Clinical presentation and serological results of the first confirmed case of yaws since the 1970s and first whole Treponema pallidum subspecies pertenue (TPE) genome from Liberia. A) Papillomatous yaws lesion below the right knee. B) Paired serological results from this case. Dual path platform syphilis lateral flow assay (ChemBio, https://chembio.com) shows antibody binding to treponemal and nontreponemal antigen indicative of active yaws infection. A complete genome sequence was recovered from this case (Figure 3).

Figure 1. Clinical presentation and serological results of the first confirmed case of yaws since the 1970s and first whole Treponema pallidum subspecies pertenue (TPE) genome from Liberia. A) Papillomatous yaws lesion below the right knee. B) Paired serological results from this case. Dual path platform syphilis lateral flow assay (ChemBio, https://chembio.com) shows antibody binding to treponemal and nontreponemal antigen indicative of active yaws infection. A complete genome sequence was recovered from this case (Figure 3).

Main Article

1These senior authors contributed equally to this article.

Page created: January 13, 2021
Page updated: March 18, 2021
Page reviewed: March 18, 2021
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