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Volume 27, Number 5—May 2021
Research

Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands

Shan Zhao, Nancy Schuurman, Wentao Li, Chunyan Wang, Lidwien A.M. Smit, Els M. Broens, Jaap A. Wagenaar, Frank J.M. van Kuppeveld, Berend-Jan Bosch, and Herman EgberinkComments to Author 
Author affiliation: Utrecht University, Utrecht, the Netherlands

Main Article

Figure 2

Serologic analyses of cat and dog serum samples from SARS-CoV-2–exposed cohort, the Netherlands. A) ELISA against SARS-CoV-2 S1, RBD, and N proteins, and VN analysis with SARS-CoV-2 pseudotyped virus. Dots indicate cat serum samples (n = 44) and triangle indicates dog sample (n = 1). B) Combination of results tested by different assays expressed as a heatmap. Dotted lines indicate positive cutoff levels. IC50, 50% inhibitory concentration; N, nucleocapsid; OD, optical density; RBD, receptor-binding domain; S1, spike protein subunit 1; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VN, virus neutralization.

Figure 2. Serologic analyses of cat and dog serum samples from SARS-CoV-2–exposed cohort, the Netherlands. A) ELISA against SARS-CoV-2 S1, RBD, and N proteins, and VN analysis with SARS-CoV-2 pseudotyped virus. Dots indicate cat serum samples (n = 44) and triangle indicates dog sample (n = 1). B) Combination of results tested by different assays expressed as a heatmap. Dotted lines indicate positive cutoff levels. IC50, 50% inhibitory concentration; N, nucleocapsid; OD, optical density; RBD, receptor-binding domain; S1, spike protein subunit 1; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; VN, virus neutralization.

Main Article

Page created: February 21, 2021
Page updated: April 20, 2021
Page reviewed: April 20, 2021
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