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Volume 27, Number 5—May 2021

Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands

Shan Zhao, Nancy Schuurman, Wentao Li, Chunyan Wang, Lidwien A.M. Smit, Els M. Broens, Jaap A. Wagenaar, Frank J.M. van Kuppeveld, Berend-Jan Bosch, and Herman EgberinkComments to Author 
Author affiliation: Utrecht University, Utrecht, the Netherlands

Main Article

Table 1

Percentage amino acid identity of canine and feline coronavirus spike and nucleocapsid proteins with SARS-CoV-2 proteins, the Netherlands*

Genus Virus SARS-CoV-2
Betacoronavirus CRCoV 32.4 28.5 20.0 15.6
Alphacoronavirus FCoV type I 29.0 24.0 16.8 7.7
Alphacoronavirus FcoV type II 27.8 25.3 17.7 8.9
Alphacoronavirus CCoV 28.0 25.1 16.9 8.9

*SARS-CoV-2, CRCoV, FCoV type I, FCoV type II, CCoV (GB: NC_045512.2, JX860640.1, FJ938060.1, AY994055.1, KC175341.1). Amino acid sequences were aligned by using Clustal W (, and pairwise identities were calculated by using the needle method in the EMBOSS pairwise alignment algorithms program ( CCoV, canine coronavirus; CRCoV, canine respiratory coronavirus; FCoV, feline coronavirus, N, nucleocapsid protein; RBD, receptor-binding domain; S, spike protein; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; S1, spike protein subunit 1.

Main Article

Page created: February 21, 2021
Page updated: April 20, 2021
Page reviewed: April 20, 2021
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