Volume 28, Number 1—January 2022
Systematic Genomic and Clinical Analysis of Severe Acute Respiratory Syndrome Coronavirus 2 Reinfections and Recurrences Involving the Same Strain
|Pt||Age, y/sex||Underlying conditions||PCR date, 1st/2nd episode||PCR Ct value–N2 gene, 1st/2nd episode||Interinfection period, d||Symptoms, 1st/2nd episode†||Serologic results, 1st/2nd episode (AU/mL)||SARS-CoV-2 variant, 2nd episode|
|1||68/M||HT||2020 Aug 12/2020 Dec 4||15/28||114||Asymptomatic/ asymptomatic||+ (56.8)/+ (76.8)||Z.1|
|2||70/F||HBP, obesity||2020 Mar 25/2020 Jun 10||31/27||77||Bilateral pneumonia/ dyspnoea||NA/+ (1,967.1)||A.5|
|3||93/F||HBP, CKD||2020 Apr 17/2020 Jun 11||31/19||55||Diarrhea/NA||–/NA||A.5|
2020 Mar 10/2020 Jun 19
Bilateral pneumonia/ diarrhea, fever
+ (415.4)/+ (636.3)
*BMT, bone marrow transplant; CKD, chronic kidney disease; HBP, high blood pressure; HT, heart transplant; N2, nucleocapsid; NA, not available; Pt, patient; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2. †The definition of the severity of the patients has been organized according to the following criteria: Mild—general malaise, cough, diarrhea, headache, fever, anosmia, dysgeusia, myalgia, rhinorrhea; moderate—previous symptoms plus dyspnea, mild respiratory failure, or unilateral pneumonia, severe—previous symptoms plus bilateral pneumonia.
1These senior authors contributed equally to this article.
2Members of the Gregorio Marañón Microbiology-ID COVID 19 Study Group are listed at the end of this article.