Wild Boars as Reservoir of Highly Virulent Clone of Hybrid Shiga Toxigenic and Enterotoxigenic Escherichia coli Responsible for Edema Disease, France
Alexandre Perrat, Priscilla Branchu, Anouk Decors, Silvia Turci, Marie-Hélène Bayon-Auboyer, Geoffrey Petit, Vladimir Grosbois, Hubert Brugère, Frédéric Auvray
, and Eric Oswald
Author affiliations: Institut de Recherche en Santé Digestive, Université de Toulouse, Institut National de la Santé et de la Recherche Médicale, Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Ecole Nationale Vétérinaire de Toulouse, Université Paul Sabatier, Toulouse, France (A. Perrat, P. Branchu, H. Brugère, F. Auvray, E. Oswald); Office Français de la Biodiversité, Orléans, France (A. Decors); Labocea, Ploufragan, France (S. Turci, M.-H. Bayon-Auboyer); Université Clermont Auvergne INRAE, VetAgro Sup, Unité Mixte de Recherche (UMR) Epidémiologie des Maladies Animales et Zoonotiques, Saint-Genès-Champanelle, France (G. Petit); UMR Animal-Santé-Territoires-Risques-Ecosystèmes, Centre de Coopération Internationale en Recherche Agronomique pour le Développement, INRAE, Montpellier, France (G. Petit, V. Grosbois); Centre Hospitalier Universitaire de Toulouse, Hôpital Purpan, Toulouse (E. Oswald)
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Figure 7
Figure 7. Comparison of antimicrobial-resistance genes with the phylogeny of wild boar Escherichia coli O139:H1 strains in France with those of E. coli O139:H1, O141:H4, O147:H4, and O138:H14 of worldwide origin. The tree is based on the phylogeny of the strains according to their core genome. The shapes of the leaves in the tree correspond to the origin of the strains (star, wild boars; circle, other hosts), and the colors of the leaves represent their serotype. Antimicrobial-resistance genes are grouped into different categories whose names are indicated at the top, with a color code. Scale bar indicates number of substitutions per site.
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