Volume 28, Number 2—February 2022
CME ACTIVITY - Synopsis
Clinical and Laboratory Characteristics and Outcome of Illness Caused by Tick-Borne Encephalitis Virus without Central Nervous System Involvement
Petra Bogovič
, Andrej Kastrin, Stanka Lotrič-Furlan, Katarina Ogrinc, Tatjana Avšič Županc, Miša Korva, Nataša Knap, and Franc Strle
, Andrej Kastrin, Stanka Lotrič-Furlan, Katarina Ogrinc, Tatjana Avšič Županc, Miša Korva, Nataša Knap, and Franc Strle
Table 1
Demographic and clinical data on adult patients who had febrile illness caused by tick-borne encephalitis virus without central nervous system involvement at the time of evaluation, Slovenia*
| Characteristic | Value |
|---|---|
| Sex | |
| F | 51 (52.0, 41.7–62.2) |
| M |
47 (48.0, 37.8–58.3) |
| Median age, y (IQR) |
51 (37–60.75) |
| Underlying illnesses |
38 (38.8, 29.1–49.2) |
| History of tick bite† |
86 (88.7, 80.6–94.2) |
| Median incubation period, d (IQR)‡ |
6 (4–9.75) |
| Median duration of illness before first evaluation, d (IQR) |
5 (4–6) |
| Clinical manifestation | |
| Body temperature >37.5°C | 95 (96.9, 91.3–99.4) |
| Median body temperature, °C (IQR)§ | 38.3 (37.8–38.9) |
| Chills | 19 (19.4, 12.1–28.6) |
| Headache | 84 (85.7, 77.2–92.0) |
| Myalgia | 53 (54.1, 43.7–64.2) |
| Arthralgia | 42 (42.9, 32.9–53.3) |
| Gastrointestinal symptoms | 45 (45.9, 35.8–56.3) |
| Abdominal pain | 2 (2.0, 0.3–7.2) |
| Nausea, vomiting | 37 (37.8, 28.2–48.1) |
| Diarrhea | 16 (16.3, 9.6–25.2) |
| Malaise and fatigue | 96 (98.0, 92.8–99.8) |
| Respiratory symptoms | 18 (18.4, 11.3–27.5) |
| Sore throat | 11 (11.2, 5.7–19.2) |
| Cough |
10 (10.2, 5.0–18.0) |
| Median duration of illness, initial phase, d (IQR)¶ |
7 (6–8) |
| Hospitalization | |
| No. hospitalized patients | 37 (37.8, 28.2–48.1) |
| Median duration of hospitalization, d (IQR)# | 3 (1–5) |
*Values are no. (%, 95% CI) except as indicated. IQR, interquartile range. †Tick bite within 4 weeks before onset of illness. Data available for 97 patients. ‡Time (days) from tick bite to onset of illness calculated only in patients with 1 bite. Data available for 54 patients. §Highest temperature in the course of the illness. ¶Data available for 82 patients. #Data available for 33 patients.
Page created: December 02, 2021
Page updated: January 21, 2022
Page reviewed: January 21, 2022
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