Volume 28, Number 2—February 2022
CME ACTIVITY - Synopsis
Clinical and Laboratory Characteristics and Outcome of Illness Caused by Tick-Borne Encephalitis Virus without Central Nervous System Involvement
Petra Bogovič
, Andrej Kastrin, Stanka Lotrič-Furlan, Katarina Ogrinc, Tatjana Avšič Županc, Miša Korva, Nataša Knap, and Franc Strle
, Andrej Kastrin, Stanka Lotrič-Furlan, Katarina Ogrinc, Tatjana Avšič Županc, Miša Korva, Nataša Knap, and Franc Strle
Table 2
Laboratory data on adult patients who had febrile illness caused by tick-borne encephalitis virus without central nervous system involvement at the time of evaluation, Slovenia*
| Laboratory findings | Value |
|
|---|---|---|
| Median blood leukocyte count, × 109/L (IQR)† | 2.3 (1.8–3.125) | |
| Blood leukocyte count <4 × 109/L | 84 (87.5, 79.2–93.4) | |
| Blood leukocyte count >10 × 109/L |
0 (0, 0–3.8) |
|
| Median blood neutrophil count, × 109/L (IQR)‡ | 1.22 (0.9–1.7) | |
| Blood neutrophil count <1.5 × 109/L | 55 (65.5, 54.3–75.5) | |
| Blood neutrophil count >7.4 × 109/L |
0 (0, 0–4.3) |
|
| Median blood lymphocyte count, × 109/L (IQR)‡ | 0.88 (0.5–1.1) | |
| Blood lymphocyte count <1.1 × 109/L | 61 (72.6, 61.8–81.8) | |
| Blood lymphocyte count >3.5 × 109/L |
1 (1.2, 0–6.5) |
|
| Median blood monocyte count, × 109/L (IQR)‡ | 0.29 (0.2–0.4) | |
| Blood monocyte count <0.21 × 109/L | 34 (40.5, 29.9–51.8) | |
| Blood monocyte count >0.92 × 109/L |
0 (0, 0–4.3) |
|
| Median blood platelet count, × 109/L (IQR)† | 132 (110.5–157) | |
| Blood platelet count <140 × 109/L |
57 (59.4, 48.9–69.3) |
|
| Serum C-reactive protein level >5 mg/L†§ |
9 (9.4, 4.4–17.1) |
|
| Liver test results, µkat/L (IQR)¶ | ||
| Median alkaline phosphatase¶ | 0.93 (0.755–1.06) | |
| Elevated >1.92 | 0 (0, 0–4.6) | |
| Median aspartate aminotransferase# | 0.615 (0.4575–0.8325) | |
| Elevated >0.58 | 44 (55.0, 43.5–66.2) | |
| Median alanine aminotransferase# | 0.53 (0.37–0.805) | |
| Elevated >0.77 | 21 (26.3, 17.0–37.3) | |
| Median gamma-glutamyl transferase¶ | 0.37 (0.265–0.595) | |
| Elevated >0.92 | 9 (11.4, 5.3–20.5) | |
| Median lactate dehydrogenase** | 3.48 (2.92–4.82) | |
| Elevated >4.13 |
12 (36.4, 20.4–54.9) |
|
| No. patients with >1 abnormal function test result†† | 50 (62.5, 51.0–73.1) |
|
*Values are no. (%, 95% CI) unless otherwise noted. IQR, interquartile range. †Data available for 96 patients. ‡Data available for 84 patients. §Median 7, range 6–45. ¶Data available for 79 patients. #Data available for 80 patients. **Data available for 33 patients. ††Data available for 80 patients.
Page created: December 02, 2021
Page updated: January 21, 2022
Page reviewed: January 21, 2022
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