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Volume 28, Number 2—February 2022
CME ACTIVITY - Synopsis

Clinical and Laboratory Characteristics and Outcome of Illness Caused by Tick-Borne Encephalitis Virus without Central Nervous System Involvement

Petra BogovičComments to Author , Andrej Kastrin, Stanka Lotrič-Furlan, Katarina Ogrinc, Tatjana Avšič Županc, Miša Korva, Nataša Knap, and Franc Strle
Author affiliations: University Medical Center Ljubljana, Ljubljana, Slovenia (P. Bogovič, S. Lotrič-Furlan, K. Ogrinc, F. Strle); University of Ljubljana, Faculty of Medicine, Ljubljana (A. Kastrin, T. Avšič Županc, M. Korva, N. Knap)

Main Article

Table 2

Laboratory data on adult patients who had febrile illness caused by tick-borne encephalitis virus without central nervous system involvement at the time of evaluation, Slovenia*

Laboratory findings Value
Median blood leukocyte count, × 109/L (IQR)† 2.3 (1.8–3.125)
Blood leukocyte count <4 × 109/L 84 (87.5, 79.2–93.4)
Blood leukocyte count >10 × 109/L
0 (0, 0–3.8)
Median blood neutrophil count, × 109/L (IQR)‡ 1.22 (0.9–1.7)
Blood neutrophil count <1.5 × 109/L 55 (65.5, 54.3–75.5)
Blood neutrophil count >7.4 × 109/L
0 (0, 0–4.3)
Median blood lymphocyte count, × 109/L (IQR)‡ 0.88 (0.5–1.1)
Blood lymphocyte count <1.1 × 109/L 61 (72.6, 61.8–81.8)
Blood lymphocyte count >3.5 × 109/L
1 (1.2, 0–6.5)
Median blood monocyte count, × 109/L (IQR)‡ 0.29 (0.2–0.4)
Blood monocyte count <0.21 × 109/L 34 (40.5, 29.9–51.8)
Blood monocyte count >0.92 × 109/L
0 (0, 0–4.3)
Median blood platelet count, × 109/L (IQR)† 132 (110.5–157)
Blood platelet count <140 × 109/L
57 (59.4, 48.9–69.3)
Serum C-reactive protein level >5 mg/L†§
9 (9.4, 4.4–17.1)
Liver test results, µkat/L (IQR)¶
Median alkaline phosphatase¶ 0.93 (0.755–1.06)
Elevated >1.92 0 (0, 0–4.6)
Median aspartate aminotransferase# 0.615 (0.4575–0.8325)
Elevated >0.58 44 (55.0, 43.5–66.2)
Median alanine aminotransferase# 0.53 (0.37–0.805)
Elevated >0.77 21 (26.3, 17.0–37.3)
Median gamma-glutamyl transferase¶ 0.37 (0.265–0.595)
Elevated >0.92 9 (11.4, 5.3–20.5)
Median lactate dehydrogenase** 3.48 (2.92–4.82)
Elevated >4.13
12 (36.4, 20.4–54.9)
No. patients with >1 abnormal function test result†† 50 (62.5, 51.0–73.1)

*Values are no. (%, 95% CI) unless otherwise noted. IQR, interquartile range. †Data available for 96 patients. ‡Data available for 84 patients. §Median 7, range 6–45. ¶Data available for 79 patients. #Data available for 80 patients. **Data available for 33 patients. ††Data available for 80 patients.

Main Article

Page created: December 02, 2021
Page updated: January 21, 2022
Page reviewed: January 21, 2022
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