Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 28, Number 7—July 2022
Dispatch

Anncaliia algerae Microsporidiosis Diagnosed by Metagenomic Next-Generation Sequencing, China

Chen Liu1, Qin Chen1, Ping Fu, and Yun-Ying ShiComments to Author 
Author affiliations: West China Hospital of Sichuan University, Chengdu, China (C. Liu, Q. Chen, P. Fu, Y.-Y. Shi); Chengdu 363 Hospital of Southwest Medical University, Chengdu (Q. Chen)

Main Article

Figure 1

Clinical course of a 45-year-old patient with Anncaliia algerae microsporidia infection, China. The upper section of the graph shows the body-temperature curve (black line); dotted black line indicates 37.2°, the upper limit of normal body temperature. Thick blue and green lines indicate medications administered; dashed thick blue line indicates a dosing frequency of every other day. Major events during the patient’s course are indicated by arrows on the x-axis. Asterisk on day 34 denotes the initial light microscopy, which failed to detect A. algerae spores. BALF, bronchoalveolar lavage fluid; CFP/SBT, cefoperazone/sulbactum; CT, computed tomography; FB, fiberoptic bronchoscopy; GCV, ganciclovir; GI, gastrointestinal; HD, hemodialysis; LM, light microscopy; MEM, meropenem; mNGS, metagenomic next-generation sequencing; MRI, magnetic resonance imaging; MXF, moxifloxacin; PIP/SBT, piperacillin/sulbactum; SMZ/TMP, sulfamethoxazole/trimethoprim; TEM, transmission electron microscopy.

Figure 1. Clinical course of a 45-year-old patient with Anncaliia algerae microsporidia infection, China. The upper section of the graph shows the body-temperature curve (black line); dotted black line indicates 37.2°, the upper limit of normal body temperature. Thick blue and green lines indicate medications administered; dashed thick blue line indicates a dosing frequency of every other day. Major events during the patient’s course are indicated by arrows on the x-axis. Asterisk on day 34 denotes the initial light microscopy, which failed to detect A. algerae spores. BALF, bronchoalveolar lavage fluid; CFP/SBT, cefoperazone/sulbactum; CT, computed tomography; FB, fiberoptic bronchoscopy; GCV, ganciclovir; GI, gastrointestinal; HD, hemodialysis; LM, light microscopy; MEM, meropenem; mNGS, metagenomic next-generation sequencing; MRI, magnetic resonance imaging; MXF, moxifloxacin; PIP/SBT, piperacillin/sulbactum; SMZ/TMP, sulfamethoxazole/trimethoprim; TEM, transmission electron microscopy.

Main Article

1These first authors contributed equally to this article.

Page created: May 16, 2022
Page updated: June 18, 2022
Page reviewed: June 18, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external