Volume 28, Number 7—July 2022
Dispatch
Anncaliia algerae Microsporidiosis Diagnosed by Metagenomic Next-Generation Sequencing, China
Figure 1

Figure 1. Clinical course of a 45-year-old patient with Anncaliia algerae microsporidia infection, China. The upper section of the graph shows the body-temperature curve (black line); dotted black line indicates 37.2°, the upper limit of normal body temperature. Thick blue and green lines indicate medications administered; dashed thick blue line indicates a dosing frequency of every other day. Major events during the patient’s course are indicated by arrows on the x-axis. Asterisk on day 34 denotes the initial light microscopy, which failed to detect A. algerae spores. BALF, bronchoalveolar lavage fluid; CFP/SBT, cefoperazone/sulbactum; CT, computed tomography; FB, fiberoptic bronchoscopy; GCV, ganciclovir; GI, gastrointestinal; HD, hemodialysis; LM, light microscopy; MEM, meropenem; mNGS, metagenomic next-generation sequencing; MRI, magnetic resonance imaging; MXF, moxifloxacin; PIP/SBT, piperacillin/sulbactum; SMZ/TMP, sulfamethoxazole/trimethoprim; TEM, transmission electron microscopy.
1These first authors contributed equally to this article.