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Volume 29, Number 10—October 2023

Research

Stability of Monkeypox Virus in Body Fluids and Wastewater

Claude Kwe Yinda1, Dylan H. Morris1, Robert J. Fischer, Shane Gallogly, Zachary A. Weishampel, Julia R. Port, Trenton Bushmaker, Jonathan E. Schulz, Kyle Bibby, Neeltje van Doremalen, James O. Lloyd-Smith, and Vincent J. MunsterComments to Author 
Author affiliations: National Institute of Allergy and Infectious Diseases, Laboratory of Virology, Hamilton, Montana, USA (C.K. Yinda, R.J. Fischer, S. Gallogly, Z.A. Weishampel, J.R. Port, T. Bushmaker, J.E. Schulz, N. van Doremalen, V.J. Munster); University of California, Los Angeles, California, USA (D.H. Morris, J.O. Lloyd-Smith); University of Notre Dame, Notre Dame, Indiana, USA (K. Bibby)

Main Article

Figure 3

Monkeypox virus decay in different human serum dilutions in Dulbecco modified Eagle medium. A) Regression lines showing predicted exponential decay of virus titers over time compared with measured (directly inferred) virus titers. Points show posterior median measured titers; black lines show 95% credible intervals. Colored lines indicate random draws from joint posterior distribution of the exponential decay rate (negative of the slope) and intercept (initial virus titer), visualizing range of possible decay patterns for each experimental condition. B) Inferred virus half-lives by condition and state. Dots show posterior median half-life estimate and black lines show 68% (thick) and 95% (thin) credible intervals. Violin plots show the shape of posterior distribution of virus half-lives.

Figure 3. Monkeypox virus decay in different human serum dilutions in Dulbecco modified Eagle medium. A) Regression lines showing predicted exponential decay of virus titers over time compared with measured (directly inferred) virus titers. Points show posterior median measured titers; black lines show 95% credible intervals. Colored lines indicate random draws from joint posterior distribution of the exponential decay rate (negative of the slope) and intercept (initial virus titer), visualizing range of possible decay patterns for each experimental condition. B) Inferred virus half-lives by condition and state. Dots show posterior median half-life estimate and black lines show 68% (thick) and 95% (thin) credible intervals. Violin plots show the shape of posterior distribution of virus half-lives.

Main Article

1These authors contributed equally to this study.

Page created: August 03, 2023
Page updated: September 20, 2023
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