Posttransfusion Sepsis Attributable to Bacterial Contamination in Platelet Collection Set Manufacturing Facility, United States
Ian Kracalik, Alyssa G. Kent, Carlos H. Villa, Paige Gable, Pallavi Annambhotla, Gillian McAllister, Deborah Yokoe, Charles R. Langelier, Kelly Oakeson, Judith Noble-Wang, Orieji Illoh, Alison Laufer Halpin, Anne F. Eder, and Sridhar V. Basavaraju
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (I. Kracalik, A.G. Kent, P. Gable, P. Annambhotla, G. McAllister, J. Noble-Wang, A.L. Halpin, S.V. Basavaraju); Food and Drug Administration, Silver Spring, Maryland, USA (C.H. Villa, O. Illoh, A.F. Eder); University of California San Francisco School of Medicine, San Francisco, California, USA (D. Yokoe, C.R. Langelier); Utah Department of Health, Salt Lake City, Utah, USA (K. Oakeson)
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Figure 5
Figure 5. Public Staphylococcus saprophyticus genomes and study isolates from investigation of bacterial contamination of platelet blood products, United States, 2018–2022. Shown is a RaxML (https://cme.h-its.org)‒generated phylogeny based on 1,808 core genes of all S. saprophyticus isolates from this study and all S.saprophyticus genomes from the National Center for Biotechnology Information RefSeq (https://www.ncbi.nlm.nih.gov/refseq) database. Isolate location, isolate source, and species from National Center for Biotechnology Information or by average nucleotide identity were layered onto the phylogeny. Light orange, blue, and purple indicate the 3 clusters from Figure 3, panel A. Black circles on branches indicate 100% support for the branch of 100 bootstraps. US states are identified by 2-letter postal codes. Scale bar indicates nucleotide substitutions per site. DR, Dominican Republic; PR, Puerto Rico.
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