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Volume 29, Number 2—February 2023
Synopsis

Changing Disease Course of Crimean-Congo Hemorrhagic Fever in Children, Turkey

Pembe Derin Oygar1, Sibel Laçinel Gürlevik, Erdal Sağ, Sare İlbay, Tekin Aksu, Osman Oğuz Demir, Yasemin Coşgun, Selin Aytaç Eyüpoğlu, Jale Karakaya, Şule Ünal Cangül, Ali Bülent Cengiz, and Yasemin ÖzsürekciComments to Author 
Author affiliations: Hacettepe University, Ankara, Turkey (P.D. Oygar, S.L. Gürlevik, E. Sağ, T. Aksu, O.O. Demir, S.A. Eyüpoğlu, J. Karakaya, Ş.Ü. Cangül, A.B. Cengiz, Y. Özsürekci); İhsan Doğramacı Children’s Hospital, Ankara (P.D. Oygar, S.L. Gürlevik, T. Aksu, O.O. Demir, S.A. Eyüpoğlu, Ş.Ü. Cangül, A.B. Cengiz, Y. Özsürekci); Ankara Training and Research Hospital, Ankara (E. Sağ); Hacettepe University Rheumatology Translational Medicine Laboratories, Ankara (S. İlbay); General Directorate of Public Health, Ministry of Health, Microbiology Reference and Biological Materials Laboratory, Ankara (Y. Coşgun)

Main Article

Table 1

Demographic and clinical characteristics, management, and outcomes of 12 pediatric case-patients with Crimean-Congo hemorrhagic fever, Turkey*

Case no. Age, y/sex Initial signs and symptoms Physical findings FFPT/PT Ribavirin duration, d IVIG duration, d Steroids duration, d Complications
1
 15/M
 Fever, myalgia, headache
 HSM, petechia
 +/+
 9
 5
 8
 Transient bradycardia
2
 7/F
 Fever, malaise, nausea
 HSM, petechia, somnolence
 +/+
 10
 5
 10
 Transient adrenal insufficiency
3
12/M
 Fever, headache, myalgia
 HSM
 +/−
 7
 1
 3
 None
4
 8/M
 Fever, malaise, nausea
 HSM, petechia, confusion
 +/+
 2
 4
 10
 Transient bradycardia
5
 10/F
 Fever, headache
 HSM
 +/−
 5
 1
 10
 None
6
 13/M
 Fever, headache
 HSM, petechia
 +/−
 5
 1
 9
 Transient bradycardia
7
 15/M
 Fever
 HSM
 +/−
 5
 1
 5
 Transient bradycardia
8
 15/M
 Fever, somnolence
 HSM, petechia, confusion
 +/−
 4
 1
 8
 Transient bradycardia
9
 11/M
 Fever, malaise
 HSM, petechia
 +/−
 5
 5
 10
 Transient bradycardia, transient adrenal insufficiency
10
 15.5/M
 Fever, headache, vomiting, diarrhea
 HSM
 +/−
 5
 1
 5
 Transient bradycardia
11
 14/M
 Fever, vomiting, diarrhea
 HSM, petechia
 +/−
 5
 1
 5
 Transient bradycardia
12 7/F Fever, malaise HSM, petechia +/+ 5 1 5 None

*All 12 case-patients survived. IVIG, intravenous immunoglobulin; FFPT, fresh frozen plasma transfusion; PT, platelet transfusion; HSM, hepatosplenomegaly; +, transfusion administered; –, transfusion not administered.

Main Article

1Current affiliation: Nicosia State Hospital, Burhan Nalbantoglu General Hospital, Nicosia, Cyprus.

Page created: December 07, 2022
Page updated: January 21, 2023
Page reviewed: January 21, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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