Volume 29, Number 4—April 2023
CME ACTIVITY - Synopsis
Pediatric Invasive Meningococcal Disease, Auckland, New Zealand (Aotearoa), 2004–2020
Cameron Burton
, Emma Best, Matthew Broom, Helen Heffernan, Simon Briggs, and Rachel Webb
, Emma Best, Matthew Broom, Helen Heffernan, Simon Briggs, and Rachel Webb
Table 1
Demographic and clinical factors of 319 confirmed cases of invasive meningococcal disease in children <15 years of age, Auckland, New Zealand, 2004–2020*
| Variable |
Total no. (missing data) |
No. (%) cases |
Average incidence, cases/100,000 population/y |
|
| Age, y | 319 (0) | |||
| <1 y | 118 (37.0) | 31.5 | ||
| 1–4 | 120 (37.6) | 8.2 | ||
| 5–9 | 46 (14.4) | 2.6 | ||
| 10–14 |
35 (11.0) |
2.0 |
||
| Sex | 319 (0) | |||
| F | 125 (39.2) | 4.8 | ||
| M |
194 (60.8) |
7.0 |
||
| Ethnicity, prioritized | 319 (0) | |||
| Māori | 114 (35.7) | 11.6 | ||
| Pacific | 140 (43.9) | 13.4 | ||
| Non-Māori, non-Pacific |
65 (20.4) |
1.9 |
||
| New Zealand Index of Deprivation Quintile† | 317‡ | |||
| 1 | 11 (3.5) | NA | ||
| 2 | 21 (6.6) | NA | ||
| 3 | 42 (13.2) | NA | ||
| 4 | 54 (17.0) | NA | ||
| 5 |
189 (59.6) |
NA |
||
| Clinical manifestations | 319 (0) | |||
| Bacteremia only | 108 (33.9) | NA | ||
| Meningitis only | 63 (19.7) | NA | ||
| Meningitis with bacteremia | 138 (42.3) | NA | ||
| Septic arthritis only | 5 (1.6) | NA | ||
| Septic arthritis with bacteremia | 2 (0.6) | NA | ||
| Meningitis and septic arthritis with bacteremia |
3 (0.9) |
NA |
||
| Vital signs on first presentation | ||||
| Temperature >38·5°C or <36°C | 314 (5) | 150 (47.7) | NA | |
| Systolic hypotension for age | 218 (101) | 84 (38.5) | NA | |
| Impaired level of consciousness |
291 (28) |
99 (34.0) |
NA |
|
| Clinical signs at first presentation | ||||
| Rash in cases with bacteremia | 248 (3) | 213 (85.9) | NA | |
| Includes purpura | 213 (3) | 108 (50.7) | NA | |
| Includes petechiae without purpura | 213 (3) | 86 (40.4) | NA | |
| Blanching only | 213 (3) | 19 (8.9) | NA | |
| Meningism in cases with meningitis | 184 (20) | 111 (60.3) | NA | |
| Bulging fontanelle in infants with meningitis | 43 (39) | 19 (44.2) | NA | |
| Arthritis during admission | 314 (5) | 19 (6.1) | NA | |
| Arthralgia during admission |
314 (5) |
23 (7.3) |
NA |
|
| *NA, not applicable. †Each NZDep quintile contains ≈20% of the population. 1 = least deprived; 5 = most deprived. ‡Two overseas cases were excluded. |
||||
Page created: February 01, 2023
Page updated: March 16, 2023
Page reviewed: March 16, 2023
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