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Volume 29, Number 4—April 2023
CME ACTIVITY - Synopsis

Pediatric Invasive Meningococcal Disease, Auckland, New Zealand (Aotearoa), 2004–2020

Cameron BurtonComments to Author , Emma Best, Matthew Broom, Helen Heffernan, Simon Briggs, and Rachel Webb
Author affiliations: The University of Auckland, Auckland, New Zealand (C. Burton, E. Best, R. Webb); Te Whatu Ora Counties Manukau, Auckland (C. Burton, R. Webb); Te Whatu Ora Te Toka Tumai Auckland, Auckland (E. Best, S. Briggs, R. Webb); Te Whatu Ora Waitematā, Auckland (M. Broom); Institute of Environmental Science and Research, Wellington, New Zealand (H. Heffernan).

Main Article

Table 3

Univariate logistic regression for combined outcome of death or sequelae in 271 confirmed cases of invasive meningococcal disease in children <15 years of age, Auckland, New Zealand, 2004–2020*

Variable
 No. cases (%)
 OR (95% CI)
 p value
Ethnicity, compared with non-Māori, non-Pacific population
Pacific 38/118 (32.2) 2.91 (1.31–7.18) 0.0128
Māori
 28/96 (29.2)
 2.52 (1.10–6.35)
 0.0366
Reduced penicillin susceptibility
 12/64 (18.8)
 0.548 (0.25–1.14)
 0.117
NZDep quintile†
 271
 1.21 (0.95–1.58)
 0.142
Age, mo†
 271
 0.996 (0.99–1.00)
 0.157
Serogroup, compared with MenB
MenC 7/18 (38.9) 1.80 (0.64–4.82) 0.247
MenW 6/25 (24.0) 0.89 (0.31–2.24) 0.822
MenY
 3/8 (37.5)
 1.70 (0.34–7.16)
 0.478
Male sex, compared with female
 50/168 (29.8)
 1.39 (0.80–2.48)
 0.248
Season, compared with autumn
Spring 23/76 (30.3) 1.47 (0.64–3.60) 0.374
Summer 11/35 (31.4) 1.56 (0.57–4.31) 0.386
Winter
 30/116 (25.9)
 1.19 (0.54–2.79)
 0.683
MeNZB vaccination, compared with fully vaccinated
Unvaccinated 43/166 (25.9) 0.76 (0.39–1.51) 0.425
Partially vaccinated
 12/41 (29.3)
 0.90 (0.37–2.17)
 0.817
Prehospital parenteral antibiotic treatment
 10/44 (22.7)
 0.79 (0.35–1.64)
 0.537
Sepsis criteria 39/145 (26.9) 1.14 (0.51–2.77) 0.751

*Men, Neisseria meningitidis serogroup; OR, odds ratio; NZDep, New Zealand Index of Deprivation
†Continuous variable; OR represents increase in odds for each unit increase in variable.

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Page created: February 01, 2023
Page updated: March 16, 2023
Page reviewed: March 16, 2023
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