Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 29, Number 6—June 2023
Dispatch

Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung

Kenrie P.Y. Hui, John C.W. Ho, Ka-Chun Ng, Samuel M.S. Cheng, Ko-Yung Sit, Timmy W.K. Au, Leo L.M. Poon, John M. Nicholls, Malik Peiris, and Michael C.W. ChanComments to Author 
Author affiliations: The University of Hong Kong School of Public Health, Hong Kong, China (K.P.Y. Hui, J.C.W. Ho, K.-C. Ng, S.M.S. Cheng, L.L.M. Poon, M. Peiris, M.C.W. Chan); Centre for Immunology and Infection, Hong Kong (K.P.Y. Hui, J.C.W. Ho, L.L.M. Poon, M. Peiris, M.C.W. Chan); The University of Hong Kong Division of Cardiothoracic Surgery, Hong Kong (K.-Y. Sit, T.W.K. Au); The University of Hong Kong School of Clinical Medicine, Hong Kong (J.M. Nicholls)

Main Article

Figure 2

Tissue tropism of influenza A viruses in ex vivo cultures of human bronchus and lung tissue. Immunohistochemical staining of influenza A nucleoprotein in ex vivo cultures of human bronchial tissues (A) and lung tissues (B) at 48 hours postinfection with H9N2/Y280, pH1N1, H3N8/MP16, novel H3N8, and H5N1/483 viruses. Positive cells are indicated by red-brown color. Images are representative of 3 individual donors. Scale bar indicates 100 μm. Detailed information on viruses used in study is provided in the Appendix .

Figure 2. Tissue tropism of influenza A viruses in ex vivo cultures of human bronchus and lung tissue. Immunohistochemical staining of influenza A nucleoprotein in ex vivo cultures of human bronchial tissues (A) and lung tissues (B) at 48 hours postinfection with H9N2/Y280, pH1N1, H3N8/MP16, novel H3N8, and H5N1/483 viruses. Positive cells are indicated by red-brown color. Images are representative of 3 individual donors. Scale bar indicates 100 μm. Detailed information on viruses used in study is provided in the Appendix .

Main Article

Page created: March 29, 2023
Page updated: May 17, 2023
Page reviewed: May 17, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external