Evolution of Avian Influenza Virus (H3) with Spillover into Humans, China
Jiaying Yang
1, Ye Zhang
1, Lei Yang
1, Xiyan Li, Hong Bo, Jia Liu, Min Tan, Wenfei Zhu, Yuelong Shu
, and Dayan Wang
Author affiliations: National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Key Laboratory for Medical Virology, Beijing, China (J. Yang, Y. Zhang, L. Yang, X. Li, H. Bo, J. Liu, M. Tan, W. Zhu, D. Wang); School of Public Health (Shenzhen), Shenzhen campus of Sun Yat-sen University, Shenzhen, China (J. Yang, Y. Shu); Institute of Pathogen Biology of Chinese Academy of Medical Science/Peking Union Medical College, Beijing (Y. Shu)
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Figure 3
Figure 3. Maximum-likelihood phylogenetic tree of avian influenza virus subtype N8 genes from China (n = 1,106) and reference sequences from GISAID (https://www.gisaid.org). Blue tree sections indicate sequences of H3 subtype viruses reported in this study; red tree sections indicate other H3 subtype viruses from China. For of clarity, some clades are collapsed. Representative clusters are indicated in shaded boxes and magnified on the right. Violet arrows indicate human H3N8 viruses; purple solid circle indicates human H10N8 virus. The phylogenetic tree of N8 genes with more complete information is shown in Appendix Figure 2, panel D). Scale bar indicates nucleotide substitutions per site.
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