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Volume 29, Number 6—June 2023
CME ACTIVITY - Synopsis

Neurologic Complications of Babesiosis, United States, 2011–2021

Sara Locke1, Jane O’Bryan1, Adeel S. Zubair, Melissa Rethana, Anne Spichler Moffarah, Peter J. Krause2, and Shelli F. Farhadian2Comments to Author 
Author affiliations: Yale School of Medicine, New Haven, Connecticut, USA (S. Locke, J. O’Bryan, A.S. Zubair, M. Rethana, A. Spichler Moffarah, P.J. Krause, S.F. Farhadian); Frank H. Netter MD School of Medicine at Quinnipiac University, North Haven, Connecticut, USA (J. O’Bryan); Yale School of Public Health, New Haven (P.J. Krause, S.F. Farhadian).

Main Article

Table 1

Neurologic symptoms during hospital admissions for babesiosis in patients admitted to Yale-New Haven Hospital, New Haven, Connecticut, USA, January 2011–October 2021*

Neurologic symptom No. (%) patients Peak parasitemia, no. (%) patients
 p value
<1.0%, n = 45 1.0%–10.0%, n = 81 >10.0%, n = 37
Headache 52 (31.9) 14 (31.1) 28 (34.6) 10 (27.0) 0.711
Confusion/delirium 27 (16.6) 2 (4.4) 13 (16.1) 12 (32.4) 0.003
Impaired consciousness 24 (14.7) 4 (8.9) 9 (11.1) 11 (29.7) 0.018
Ataxia/gait disorder 17 (10.4) 3 (6.7) 10 (12.4) 4 (10.8) 0.632
Vision impairment 10 (6.1) 5 (11.1) 4 (4.9) 1 (2.7) 0.266
Acute syncope 6 (3.7) 2 (4.4) 4 (4.9) 0 (0.0) 0.482
Language deficit 5 (3.1) 0 (0.0) 5 (6.2) 0 (0.0) 0.106
Nerve pain 4 (2.5) 1 (2.2) 2 (2.5) 1 (2.7) 1.000
Focal weakness 3 (1.8) 1 (2.2) 1 (1.2) 1 (2.7) 0.794
Tremor 3 (1.8) 1 (2.2) 2 (2.5) 0 (0.0) 1.000
Seizure 2 (1.3) 1 (2.2) 0 (0.0) 1 (2.7) 0.252

*Total sample (n = 163); Column percentages do not sum to 100% due to many patients being affected by multiple neurologic conditions throughout hospitalization. Boldface type indicates statistical significance.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: April 13, 2023
Page updated: May 19, 2023
Page reviewed: May 19, 2023
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